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Group Sequential and Confirmatory Adaptive Designs in Clinical Trials
This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs. Confirmatory adaptive designs are a generalization of group sequential designs. With these designs, interim analyses are performed in order to stop the trial prematurely under control of the Type I error rate. In adaptive designs, it is also permissible to perform a data-driven…
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- ISBN/ISSN
- 978-3-319-32560-6
- Collation
- XVI, 301
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A Guide to Reproduction Social Issues and Human Concerns
The purpose of this comprehensive text is to increase awareness of human reproduction and its consequences. The central theme links reproductive capacity, the social consequences of the multiple stresses this places on the environment and the ways this relates back to the reproductive health of humans and other animals. In the first section, the biology of human reproduction is discussed, inclu…
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- ISBN/ISSN
- 9780511608582
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- -
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Uncertainty in Biology A Computational Modeling Approach
Computational modeling allows to reduce, refine and replace animal experimentation as well as to translate findings obtained in these experiments to the human background. However these biomedical problems are inherently complex with a myriad of influencing factors, which strongly complicates the model building and validation process. This book wants to address four main issues related to the bu…
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- ISBN/ISSN
- 978-3-319-21296-8
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A General View of the Writings of Linnaeus
Carl Linnaeus (1707–88), father of modern taxonomy, was one of the most important scientists of the eighteenth century. This biography was written by Richard Pulteney (1730–1801), a physician and botanist who greatly admired Linnaeus' methods and aimed to promote them in England. The first edition was published in 1781 and contains a thorough account of the major works of Linnaeus and his u…
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- William George Maton
- ISBN/ISSN
- 9781139095945
- Collation
- -
- Series Title
- Cambridge Library Collection - Botany and Horticulture
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A General History of Quadrupeds
Thomas Bewick (1753–1828) began his career as an apprentice to the engraver and businessman Ralph Beilby (1743–1817). Having entered into a partnership and illustrated more than eighty small books for children, they decided to work together on this natural history, with Beilby drafting the descriptions and Bewick providing wood engravings and textual revisions. It was first published in 179…
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- ISBN/ISSN
- 9781139854702
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- -
- Series Title
- Cambridge Library Collection - Zoology
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A Garden of Pleasure
Eleanor Vere Boyle (1825–1916), who re-created the gardens of Huntercombe Manor in Berkshire in the 1870s, was a talented artist as well as an author, illustrating both poetry and books for children. Coming from an aristocratic family, and in later life a friend of Queen Alexandra, she produced sketches and watercolours admired by Ruskin and Landseer, and Tennyson and Bulwer Lytton contribute…
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- ISBN/ISSN
- 9781107741805
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- -
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- Cambridge Library Collection - Botany and Horticulture
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A Framework for Community Ecology
This book addresses an important problem in ecology: how are communities assembled from species pools? This pressing question underlies a broad array of practical problems in ecology and environmental science, including restoration of damaged landscapes, management of protected areas, and protection of threatened species. This book presents a simple logical structure for ecological assembly and…
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- 9781009067881
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- -
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A Fossil History of Southern African Land Mammals
This reference provides comprehensive information on the taxonomy and distribution in time and space of all currently recognized southern African fossil mammals. After an introductory background chapter on southern Africa, mammals, sites and dating, the following chapters are presented by epoch, covering the Eocene, Miocene, Pliocene, Pleistocene and Holocene. Individual maps provide informatio…
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- ISBN/ISSN
- 9781108647243
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A Flora of Cambridgeshire
This flora, published in 1964, was the first comprehensive account of Cambridgeshire's plants since Babington's of 1860. Based on records to the end of 1962, it details 1509 species. These comprise 27 pteridophytes, 3 gymnosperms, 1223 angiosperms and 256 bryophytes. The following information is provided for each of the species: scientific name; well-known vernacular name, if any; first known r…
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- ISBN/ISSN
- 9780511693427
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- -
- Series Title
- Cambridge Library Collection - Cambridge
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A First Course in Statistical Programming with R
This is the only introduction you'll need to start programming in R, the open-source language that is free to download, and lets you adapt the source code for your own requirements. Co-written by one of the R Core Development Team, and by an established R author, this book comes with real R code that complies with the standards of the language. Unlike other introductory books on the ground-brea…
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- ISBN/ISSN
- 9780511803642
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- -
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