This book explores the double coding property of DNA, which is manifested in the digital and analog information types as two interdependent codes. This double coding principle can be applied to all living systems, from the level of the individual cell to entire social systems, seen as systems of communication. Further topics discussed include the ubiquitous problem of logical typing, which refl…
This 2nd edition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years. As the previous edition, this 2nd edition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological r…
This book reviews the main concepts concerning DNA damage due to environmental carcinogens, the effects of DNA damage on DNA replication using a single DNA polymerase or DNA replisome, and the effects of carcinogens on various cell activities. It also introduces the detailed protocols for bypassing DNA damage. As we know, various environmental carcinogens are produced as a result of industry, a…
M. R. James (1862–1936) is probably best remembered as a writer of chilling ghost stories, but he was an outstanding scholar of medieval literature and palaeography, who served both as Provost of King's College, Cambridge, and as Director of the Fitzwilliam Museum, and many of his stories reflect his academic background. His detailed descriptive catalogues of manuscripts owned by colleges, ca…
This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and euka…
This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter ge…
This volume is dedicated to Prof. Dag Prawitz and his outstanding contributions to philosophical and mathematical logic. Prawitz's eminent contributions to structural proof theory, or general proof theory, as he calls it, and inference-based meaning theories have been extremely influential in the development of modern proof theory and anti-realistic semantics. In particular, Prawitz is the main…
It also covers heat-induced changes in milk, the use of exogenous enzymes in dairy processing, principal physical properties of milk, bioactive compounds in milk and comparison of milk of different species.
This book offers a systematic introduction to the engineering principles and techniques of cavitation in biomedicine on the basis of its physics and mechanism. Adopting an interdisciplinary approach, it covers areas of interest ranging from physics and engineering to the biological and medical sciences. Individual chapters introduce the fundamentals of cavitation, describe its characterization,…
Verena Brenner provides a systematic approach for the investigation, measurement, and management of supply chain disruptions. A terminological, theoretical and practical basis for the analysis of supply chain disruptions is developed to create a consistent and transferable research framework. To better understand why certain supply chains are more susceptible to disruptions than others, this fr…