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Molecular and Cellular Biology of Platelet Formation
This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and r…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-39560-9
- Collation
- X, 460
- Series Title
- -
- Call Number
- -
Molecular Therapies of Cancer
Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the t…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-13277-8
- Collation
- XV, 488
- Series Title
- -
- Call Number
- -
Molecular Targets and Strategies in Cancer Prevention
The book focuses on the understanding of molecular pathways by which normal cell progress to the definable stage of cancer. The chapters explore microbiota and chronic inflammation, multiple myeloma chemoprevention, microRNAs, cancer regulation, liquid biopsies, and angiogenesis. Recent advances of molecular risk assessment, tumor microenvironment, microneoplasia, malignant gene expressions are…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-31252-1
- Collation
- V, 180
- Series Title
- -
- Call Number
- -
Molecular Structures and Structural Dynamics of Prion Proteins and Prions
This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased infectious prions (PrPSc), using MD and MM techniques. As we all know, prion diseases, caused by…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-7317-1
- Collation
- XIX, 355
- Series Title
- Focus on Structural Biology
- Call Number
- -
Emerging Therapies in Neurorehabilitation II
This book reports on the latest technological and clinical advances in the field of neurorehabilitation. It is, however, much more than a conventional survey of the state-of-the-art in neurorehabilitation technologies and therapies. It was written on the basis of a week of lively discussions between PhD students and leading research experts during the Summer School on Neurorehabilitation (SSNR2…
- Edition
- -
- ISBN/ISSN
- 978-3-319-24901-8
- Collation
- 19 b/w illustrations, 36 illustrations in colour
- Series Title
- -
- Call Number
- -
Modified Nucleic Acids in Biology and Medicine
This volume is comprised of 18 chapters, covering various aspects of DNA modification and RNA modified bases. It also discusses in detail circular RNA, therapeutic oligonucleotides and their different properties. The chemical nature of DNA, RNA, protein and lipids makes these macromolecules easily modifiable, but they are also susceptible to damage from both endogenous and exogenous agents. …
- Edition
- 1
- ISBN/ISSN
- 2197-9758
- Collation
- XIV, 453
- Series Title
- RNA Technologies
- Call Number
- -
Modern Stroke Rehabilitation through e-Health-based Entertainment
This book describes a new, “e-Health” approach to stroke rehabilitation. The authors propose an alternative approach that combines state of the art ICT technologies ranging from Augmented and Virtual Reality gaming environments to latest advances in immersive user interfaces for delivering a mixed-reality training platform, along with advanced embedded micro sensing and computing devices e…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-21292-0
- Collation
- IX, 324
- Series Title
- -
- Call Number
- -
Molecular Mechanisms of Cell Differentiation in Gonad Development
This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of th…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-31971-1
- Collation
- XII, 434
- Series Title
- Results and Problems in Cell Differentiation
- Call Number
- -
Molecular Genetics of Pediatric Orthopaedic Disorders
In the past two decades we have seen a surge forward in understanding the genetics and biochemistry underlying many pediatric orthopaedic disorders. A few projects have even progressed into the realm of clinical trials that are primarily aimed at controlling progressive disease. Meanwhile, genomic technology development has outpaced expectations and is enabling gene discovery for disorders that…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-2168-3
- Collation
- XII, 168
- Series Title
- Springer New York, NY
- Call Number
- -
Monooxygenase, Peroxidase and Peroxygenase Properties and Mechanisms of Cytoc…
This book describes in 13 chapters mechanisms of P450 used to monooxygenate substrates via the NAD(P)H/O2 pathway using its peroxidase and peroxygenase functions. P450 also utilizes peroxides, peracids, periodate and iodosobenzene to oxygenate substrates via the shunt pathway. Also described are mechanisms used in the oxidation of pharmaceuticals by CYP3A4; acyl- carbon cleavage by CYP17A1, CYP…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-16008-5
- Collation
- XV, 368
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- -
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