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Multifaceted Roles of Crystallography in Modern Drug Discovery
The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug d…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-9718-4
- Collation
- XI, 240
- Series Title
- NATO Science for Peace and Security Series A: Chemistry and Biology
- Call Number
- -
Emotional Engineering Volume 4
This book describes the important role of emotion in a hyper-connected society and how product development and manufacture change. It explores how our work and lifestyle may be affected by forthcoming technologies and presents key research on multisensory informatics, one of the most important tools for making the most of emotion. This fourth volume of the Emotional Engineering Series focuse…
- Edition
- -
- ISBN/ISSN
- 978-3-319-29433-9
- Collation
- 40 b/w illustrations, 85 illustrations in colour
- Series Title
- -
- Call Number
- -
Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and Treatments
Over the past decade, we have made great advances in the field of multiple sclerosis (MS) research, and this book focuses on those advances in MS pathogenesis and treatment. While some of these advances have been through new approaches and ideas that have emerged in the last decade such as the newly identified protective role that amyloid proteins may play in MS or the use of helminths to treat…
- Edition
- -
- ISBN/ISSN
- 978-3-319-25543-9
- Collation
- XII, 235
- Series Title
- -
- Call Number
- -
Multi-axial Fatigue of Trabecular Bone with Respect to Normal Walking
This book focuses on the analysis and treatment of osteoporotic bone based on drug administration, tracking fatigue behavior and taking into consideration the mechanical interaction of implants with trabecular bone. Weak trabeculae are one of the most important clinical features that need to be addressed in order to prevent hip joint fractures.
- Edition
- 1
- ISBN/ISSN
- 2191-530X
- Collation
- VIII, 55
- Series Title
- SpringerBriefs in Applied Sciences and Technology
- Call Number
- -
Molecular and Cellular Mechanobiology
This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological reg…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-5615-9
- Collation
- XIII, 302
- Series Title
- Physiology in Health and Disease
- Call Number
- -
Molecular and Cellular Biology of Platelet Formation
This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and r…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-39560-9
- Collation
- X, 460
- Series Title
- -
- Call Number
- -
Molecular Therapies of Cancer
Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the t…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-13277-8
- Collation
- XV, 488
- Series Title
- -
- Call Number
- -
Molecular Targets and Strategies in Cancer Prevention
The book focuses on the understanding of molecular pathways by which normal cell progress to the definable stage of cancer. The chapters explore microbiota and chronic inflammation, multiple myeloma chemoprevention, microRNAs, cancer regulation, liquid biopsies, and angiogenesis. Recent advances of molecular risk assessment, tumor microenvironment, microneoplasia, malignant gene expressions are…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-31252-1
- Collation
- V, 180
- Series Title
- -
- Call Number
- -
Molecular Structures and Structural Dynamics of Prion Proteins and Prions
This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased infectious prions (PrPSc), using MD and MM techniques. As we all know, prion diseases, caused by…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-7317-1
- Collation
- XIX, 355
- Series Title
- Focus on Structural Biology
- Call Number
- -
Emerging Therapies in Neurorehabilitation II
This book reports on the latest technological and clinical advances in the field of neurorehabilitation. It is, however, much more than a conventional survey of the state-of-the-art in neurorehabilitation technologies and therapies. It was written on the basis of a week of lively discussions between PhD students and leading research experts during the Summer School on Neurorehabilitation (SSNR2…
- Edition
- -
- ISBN/ISSN
- 978-3-319-24901-8
- Collation
- 19 b/w illustrations, 36 illustrations in colour
- Series Title
- -
- Call Number
- -
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