This case based resource focuses on kidney disease in patients with cancer. Chapters cover the pathophysiology and management of specific kidney diseases in cancer patients, as well as the impact of chemotherapy, toxicity of organ and stem cell transplantation and other emerging therapies. Filling a significant knowledge gap in this burgeoning field, Onconephrology features the latest evidence …
This volume offers a fresh perspective on the copy and the practice of copying, two topics that, while the focus of much academic discussion in recent decades, have been underrepresented in the discourse on transculturality. Here, experts from a wide range of academic disciplines present their views on the copy from a transcultural perspective, seeking not to define the copy uniformly, but to r…
Overview: Like most introductory science textbooks, this one opens with a discussion of scientific method. A key feature is its focus on experimental support for what we know about cell and molecular biology. Understanding how science is practiced and how investigators think about experimental results is essential to understanding the relationship of cell structure and function…, not to menti…
This book provides a concise introduction to soft matter modelling. It offers an up-to-date review of continuum mechanical description of soft and biological materials from the basics to the latest scientific materials. It includes multi-physics descriptions, such as chemo-, thermo-, electro- mechanical coupling. It derives from a graduate course at Technion that has been established in recen…
This book first describes medical devices in relation to regenerative medicine before turning to a more specific topic: artificial heart technologies. Not only the pump mechanisms but also the bearing, motor mechanisms, and materials are described, including expert information. Design methods are described to enhance hemocompatibility: main concerns are reduction of blood cell damage and protei…
Well known experts in the field of Chronobiology from around the world, provide an integrative view of the state of the art of circadian biology. At present, genetic and epigenetic interaction of regulatory pathways among circadian oscillators, metabolic networks, cellular differentiation and neuronal communication are subject of intense scrutiny. The book is organized in three sections: The fi…
Thomas Jefferson famously wrote that the earth belongs to the living. His letter to James Madison is often quoted for the proposition that we should not be bound to the 'dead hand of the past', suggesting that the Constitution should instead be interpreted as a living, breathing document. Less well-known is Madison's response, in which he said the improvements made by the dead - including the U…
This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for …
This volume deals with topics such as mechanism and machine design, biomechanics and medical engineering, gears, mechanical transmissions, mechatronics, computational and experimental methods, dynamics of mechanisms and machines, micromechanisms and microactuators, and history of mechanisms and transmissions. Following MeTrApp 2011 and 2013, held under the auspices of the IFToMM, these proceed…
This monograph addresses the foundations of mechanothermodynamics and analyzes two of its key principles—damage of everything that exists has no conceivable limits, and effective energy (entropy) flows caused by loads of a different nature do not have a cumulative property; they interact dialectically. The authors examine a generalized model of energy and entropy states of a mechanothermodyna…