Neutrino Astrophysics with the ANTARES Telescope

This thesis is devoted to ANTARES, the first underwater neutrino telescope in the Mediterranean sea. As the main scientific analysis, a search for high-energy neutrino emission from the region of the Fermi bubbles has been performed using data from the ANTARES detector. A method for the background estimation using off-zones has been developed specially for this measurement. A new likelihood for…

Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP)

Phosphatases, such as TNAP are fundamental in regulating the roles of cellular, and consequently numerous body functions. TNAP is a ubiquitous enzyme with a wide spectrum of substrates and specificity. Regulation at the cellular level and the lack of TNAP activity is a lethal condition. Recent findings of a highly specific regional, laminar and subcellular localization of TNAP in the cerebral c…

Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems

The book presents a new, powerful model of neuronal networks, consisting of a three-dimensional neuronal culture in which 3D neuronal networks are coupled to micro-electrode-arrays (MEAs). It discusses the main advantages of the three-dimensional system compared to its two-dimensional counterpart, and shows that the network dynamics, recorded during both spontaneous and stimulated activity, dif…

Neural Stem Cells in Development, Adulthood and Disease

This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disea…

Netherlands Yearbook of International Law 2014

The Netherlands Yearbook of International Law was first published in 1970. It offers a forum for the publication of scholarly articles of a more general nature in the area of public international law including the law of the european Union. One of the key functions or purposes of international law (and law in general for that matter) is to provide long-term stability and legal certainty. Yet, …

Nanoporous Metals for Advanced Energy Technologies

This book covers the state-of-the-art research in nanoporous metals for potential applications in advanced energy fields, including proton exchange membrane fuel cells, Li batteries (Li ion, Li-S, and Li-O2), and supercapacitors. The related structural design and performance of nanoporous metals as well as possible mechanisms and challenges are fully addressed. The formation mechanisms of nanop…

The Water We Eat Combining Virtual Water and Water Footprints

This book pursues a comprehensive, multidisciplinary approach in order to analyze the relationship between water and food security. It demonstrates that most of the world’s economies lack sufficient water resources to secure their populations’ food requirements and are thus virtual importers of water. One of the most inspiring cases, which this book is rooted in, is Italy: the third largest…

Nanotechnology and Ethical Governance in the European Union and China

This book addresses questions surrounding the feasibility of a global approach to ethical governance of science and technology. The emergence and rapid spread of nanotechnology offers a test case for how the world might act when confronted with a technology that could transform the global economy and provide solutions to issues such as pollution, while potentially creating new environmental and…

The WTO and Food Security Implications for Developing Countries

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978-981-10-2179-4

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Near-Net Shape Manufacturing of Miniature Spur Gears by Wire Spark Erosion Ma…

This work describes an experimental investigation with the aim to evaluate and establish wire spark erosion machining (WSEM) as a viable alternative for high quality miniature gear manufacturing. External spur type miniature brass (ASTM 858) gears with 12 teeth, 9.8 mm outside diameter and 5 mm face width were manufactured by WSEM. The research work was accomplished in four distinct experimenta…