This preamble sets out to introduce the topic of international procedural law, focusing on the intellectual history of international dispute settle- ment. The leading idea is to take a picture of the major contributions to the reflection on international procedural law, starting from some mile- stone works which developed the basic ideas, the epistemic grounds of an international procedura…
This book investigates lifecycle management strategies used by pharmaceutical companies attempting to maximize the value of their product portfolio. Such strategies are sometimes referred to by generic drug companies as “evergreening”. The analysis focuses on two of these strategies, namely product improvements and product line extensions. In particular, an evaluation of the patents that fo…
This concise introduction to model theory begins with standard notions and takes the reader through to more advanced topics such as stability, simplicity and Hrushovski constructions. The authors introduce the classic results, as well as more recent developments in this vibrant area of mathematical logic. Concrete mathematical examples are included throughout to make the concepts easier to foll…
This textbook, available in two volumes, has been developed from a course taught at Harvard over the last decade. The course covers principally the theory and physical applications of linear algebra and of the calculus of several variables, particularly the exterior calculus. The authors adopt the 'spiral method' of teaching, covering the same topic several times at increasing levels of sophist…
This classic text is known to and used by thousands of mathematicians and students of mathematics throughout the world. It gives an introduction to the general theory of infinite processes and of analytic functions together with an account of the principal transcendental functions.
This self-contained introduction to algebraic topology is suitable for a number of topology courses. It consists of about one quarter 'general topology' (without its usual pathologies) and three quarters 'algebraic topology' (centred around the fundamental group, a readily grasped topic which gives a good idea of what algebraic topology is). The book has emerged from courses given at the Univer…
An extensive review of the literature on learning assessment in informal settings, expert discussion of key issues, and a new model for good assessment practice. Today educational activities take place not only in school but also in after-school programs, community centers, museums, and online communities and forums. The success and expansion of these out-of-school initiatives depends on our ab…
This concise text delivers a basic introduction to neurology and is designed for use by medical students during their rotation in neurology and related disciplines. Updated and expanded, this second edition follows the same order as the first, starting with how to approach a patient with a neurologic problem followed by the latest information on the phenomenology, pathophysiology and symptoms o…
This unique text introduces students and researchers to the world of misfolded proteins, toxic oligomers, and amyloid assemblages, and the diseases of the brain that result. During the past few years the connections between failures in protein quality control and neurological disorders have been reinforced and strengthened by discoveries on multiple fronts. These findings provide novel insights…
This authoritative book introduces and summarizes the latest models and skills required to design and fabricate nanomechanical resonators with a focus on nanomechanical sensing. It also establishes the theoretical foundation for courses on micro and nanomechanics. This book takes an applied approach to nanomechanics, providing a complete set of mechanical models, including strings and membrane …