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Urine Proteomics in Kidney Disease Biomarker Discovery
This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the…
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- ISBN/ISSN
- 978-94-017-9523-4
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- 15 b/w illustrations, 10 illustrations in colour
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Unraveling Thermoluminescence
The book is essentially about the theoretical aspects of thermoluminescence (TL). It is structured and written in a manner which will specially be of interest to the fresh undergraduate students and young researchers planning to take up work in the field of thermoluminescence. It is arranged into seven chapters, starting with the historical growth of the subject of TL and an overview of the lum…
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- ISBN/ISSN
- 978-81-322-1940-8
- Collation
- 69 b/w illustrations
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Biochemical Roles of Eukaryotic Cell Surface Macromolecules
Consists of critical reviews and original research papers from the 2014 International Symposium on the "Biochemical Role of Eukaryotic Cell Surface Macromolecules". Topics covered include: · neurochemical and biochemical analysis of cell surface glycoconjugates · membrane skeletal organization · GPCRs and other receptors · biophysical approaches to study membrane interactions · glycoconjug…
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- ISBN/ISSN
- 978-3-319-11280-0
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- Call Number
- 610.28
Biobetters : Protein Engineering to Approach the Curative
“Biobetters: Protein Engineering to Approach the Curative” discusses the optimization of protein therapeutic products for treatment of human diseases. It is based on the fact that though numerous important therapeutic protein products have been developed for life threatening and chronic diseases that possess acceptable safety and efficacy profiles, these products have generally not been ree…
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- 610.28
Drug treatment of sleep disorders
Following reviews on sleep physiology, regulation, pharmacology, and the neuronal networks regulating sleep and awakening, as well as a classification of sleep disorders, this book presents a number of major breakthroughs in the treatment of those disorders. These include recently approved drugs for treating insomnia, such as Doxepin; variations on previously approved molecules, e.g. Zolpidem s…
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- 9783319115146
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- Call Number
- 616
Long Noncoding RNAs: Structures and Functions
This book presents a common principle of actions of long noncoding RNAs (lncRNAs) from points of view at the atomic, molecular and cellular levels. At the atomic level, chemical studies of ribonucleic acids explain the chemical behavior of lncRNAs. Structural biological analysis of lncRNAs and its binding proteins also reveal the precise mechanisms of their actions. Molecular biological approac…
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- ISBN/ISSN
- 978-4-431-55576-6
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Long Non-coding RNAs in Human Disease
This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, th…
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- ISBN/ISSN
- 978-3-319-23907-1
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The Genetics of Type 2 Diabetes and Related Traits
The first section explores genome-wide association studies, the extension of this method to less accessible phenotypes and the arrival of next-generation sequencing. A further section goes beyond genetics to illustrate how other data sources can help interpret genetic data, such as leveraging population diversity, the correlation of genetic associations with physiological measurements, gene exp…
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- ISBN/ISSN
- 978-3-319-01574-3
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- XI, 576
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The Future of HIV-1 Therapeutics
This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of…
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- ISBN/ISSN
- 978-3-319-18518-7
- Collation
- X, 254
- Series Title
- Current Topics in Microbiology and Immunology
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The Floating Strip Micromegas Detector
This book discusses a novel and high-rate-capable micro pattern gaseous detector of the Micromegas (MICRO-MEsh GAS detector) type. It provides a detailed characterization of the performance of Micromegas detectors on the basis of measurements and simulations, along with an in-depth examination of analysis and reconstruction methods. The accurate and efficient detection of minimum ionizing parti…
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- ISBN/ISSN
- 978-3-319-18893-5
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- XV, 256
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- Springer Theses
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