Engineering design of microbioreactors (MBRs) and organ-on-chip (OoC) devices can take advantage of established design science theory, in which systematic evaluation of functional concepts and user requirements are analyzed.
Aging is a dynamic and irreversible physiological process, which leads to the progressive decline of biological functions involving all tissues and organs, due to a variety of endogenous and environmental factors. Metabolic changes are some of the hallmarks of aging and the alteration of metabolic pathways may accelerate the process and the onset of age-related diseases.
Scarring of the glomerular and tubulointerstitial compartments is a hallmark of progressive kidney disease and is considered a common pathway leading to end-stage of renal failure. Renal fibrosis involves a complex interplay between intrinsic kidney cells, leukocytes, and fibroblasts in which transforming growth factor-β (TGF-β) plays a key role. Inhibition of TGF-β1 suppresses renal fib…
Standard laboratory methods for measurement of soil nitrate (NO3–N) use various procedures and instruments to analyze soil samples taken from the field and transported to the laboratory
Advances in ME/CFS Research and Clinical Care spotlights Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a maligned, stigmatized, under-researched disease, which lacks a definitive, objective clinical test for its diagnosis, and definitive palliative and curative treatments. A few brave physicians attempt to alleviate the suffering of the afflicted
The use of composite materials is ubiquitous in every field of human activities, including in the agricultural, industrial, environmental, biomedical and transport sectors. After a pandemic with the simultaneous unfolding of an energy and climatic crisis, we now realize how necessary it is to carry out studies on composite materials based on polymers to positively affect our current society and…
With the development of modern society, environmental pollution and energy shortages have become the focus of attention worldwide. Most of the global energy supplies are generated from fossil fuel, which gives rise to environmental pollution and climate change. Photocatalysis technology, which can directly convert solar energy into high value-added fuel and chemical materials or degrade a wide …
Low-density lipoprotein (LDL) circulating in human bloodstream is the source of lipids that accumulate in arterial intimal cells in atherosclerosis. In-vitro–modified LDL (acetylated, exposed to malondialdehyde, oxidized with transition metal ions, etc.) is atherogenic, that is, it causes accumulation of lipids in cultured cells
In a world urgently requiring more sustainable agriculture, food security and healthier diets the demand for legume crops is on the rise. This growth is fostered by the increasing need for plant protein and for sound agricultural practices that are more adaptable and environmentally sensitive
This book is available as open access through the Bloomsbury Open Access programme and is available on www.bloomsburycollections.com. It is funded by the University of Leicester. Between 1415, when the Portuguese first used convicts for colonization purposes in the North African enclave of Ceuta, to the 1960s and the dissolution of Stalin's gulags, global powers including the Spanish, Dutch, Po…