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Multifaceted Roles of Crystallography in Modern Drug Discovery
The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug d…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-9718-4
- Collation
- XI, 240
- Series Title
- NATO Science for Peace and Security Series A: Chemistry and Biology
- Call Number
- -
Empirical Modeling and Data Analysis for Engineers and Applied Scientists
This textbook teaches advanced undergraduate and first-year graduate students in Engineering and Applied Sciences to gather and analyze empirical observations (data) in order to aid in making design decisions. While science is about discovery, the primary paradigm of engineering and "applied science" is design. Scientists are in the discovery business and want, in general, to understand the …
- Edition
- -
- ISBN/ISSN
- 978-3-319-32768-6
- Collation
- 40 b/w illustrations, 61 illustrations in colour
- Series Title
- -
- Call Number
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The Twin Sister Planets Venus and Earth Why are they so different?
This book explains how it came to be that Venus and Earth, while very similar in chemical composition, zonation, size and heliocentric distance from the Sun, are very different in surface environmental conditions. It is argued here that these differences can be accounted for by planetoid capture processes and the subsequent evolution of the planet-satellite system. Venus captured a one-half moo…
- Edition
- -
- ISBN/ISSN
- 978-3-319-11388-3
- Collation
- -
- Series Title
- -
- Call Number
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Modelling Electroanalytical Experiments by the Integral Equation Method
This comprehensive presentation of the integral equation method as applied to electro-analytical experiments is suitable for electrochemists, mathematicians and industrial chemists. The discussion focuses on how integral equations can be derived for various kinds of electroanalytical models. The book begins with models independent of spatial coordinates, goes on to address models in one dimensi…
- Edition
- 1
- ISBN/ISSN
- 978-3-662-44881-6
- Collation
- XVII, 406
- Series Title
- Monographs in Electrochemistry
- Call Number
- -
Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases
This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed ‘amyloid’. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer’s disease-related dementia and Parkinson’s disease, as well as other less prevalen…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-18364-0
- Collation
- VII, 163
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- -
Multiheme Cytochromes
This brief introduces the structural and functional characterization of this important group of proteins. The content of each chapter is aimed at the non-specialist so that key concepts, methodologies and applications can be presented in a "snapshot" style volume. Multiheme cytochromes are ever more important now that it is possible to obtain genome sequences of microorganisms which have major …
- Edition
- 1
- ISBN/ISSN
- 978-3-642-44960-4
- Collation
- XVI, 39
- Series Title
- SpringerBriefs in Molecular Science
- Call Number
- -
Molecular and Cellular Mechanobiology
This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological reg…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-5615-9
- Collation
- XIII, 302
- Series Title
- Physiology in Health and Disease
- Call Number
- -
Multi-Component and Sequential Reactions in Polymer Synthesis
The series Advances in Polymer Science presents critical reviews of the present and future trends in polymer and biopolymer science. It covers all areas of research in polymer and biopolymer science including chemistry, physical chemistry, physics, material science. The thematic volumes are addressed to scientists, whether at universities or in industry, who wish to keep abreast of the importan…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-20719-3
- Collation
- VII, 206
- Series Title
- Advances in Polymer Science
- Call Number
- -
Molecular Structures and Structural Dynamics of Prion Proteins and Prions
This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased infectious prions (PrPSc), using MD and MM techniques. As we all know, prion diseases, caused by…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-7317-1
- Collation
- XIX, 355
- Series Title
- Focus on Structural Biology
- Call Number
- -
Molecular Physiology and Ecophysiology of Sulfur
This proceedings volume contains a selection of invited and contributed papers of the 9th International Workshop on Sulfur Metabolism in Plants, which was hosted by Heinz Rennenberg, Albert-Ludwigs-University Freiburg and was held at Schloss Reinach, Freiburg-Munzigen, Germany from April 14-17, 2014. The focus of this workshop was on molecular physiology and ecophysiology of sulfur in plants an…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-20136-8
- Collation
- XIII, 265
- Series Title
- Proceedings of the International Plant Sulfur Workshop
- Call Number
- -
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