This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today’s initiatives towards precision medicine. The following chapters exp…
This volume explores microRNA pathophysiology, focusing on basic concepts in molecular and cellular biology. Chapters contributed by leading scientists examine recently discovered pathways in several processes, including aging, diabetes, cardiovascular disease, hematopoiesis, and mitochondrial fitness. The authors contextualize microRNAs within epigenetics and micropeptidomics, angiongenesis an…
The book provides fundamental new insights in the structure and function of the healthy NeuroMuscular system. Recent findings suggest that the musculoskeletal system that supports movement control on Earth is controlled by unique principles of structural, biochemical and molecular characteristics. Mechanical loading by working against normal gravity helps to support principal structures in bon…
Brehe’s Grammar Anatomy makes grammar accessible to general and specialist readers alike. This book provides an in-depth look at beginner grammar terms and concepts, providing clear examples with limited technical jargon. Whether for academic or personal use, Brehe’s Grammar Anatomy is the perfect addition to any resource library.
Supersimetri telah diusulkan sebagai ke simetri an alam yang baru. Model supersimetris fisika partikel memprediksi keadaan materi superpartner baru untuk setiap partikel yang diketahui dalam Model Standar. Keberadaan superpartner semacam itu akan memiliki implikasi yang lebih luas, dari sejarah awal Alam semesta hingga apa yang diamati pada akselerator energi tinggi seperti LHC CERN. Dalam te…
This book describes the anatomy of the posterior fossa, together with the main associated surgical techniques, which are detailed in numerous photographs and step-by-step color illustrations. The book presents approaches and surgical techniques such as the trans-cerebellomedullary fissure approach and its variation to the fourth ventricle, as well as the cerebellomedullary cistern, infratent…
This book is the first comprehensive work to be published on far-ultraviolet (FUV) and deep-ultraviolet (DUV) spectroscopy, subjects of keen interest because new areas of spectroscopy have been born in the FUV and DUV regions. For example, FUV spectroscopy in condensed matter has become possible due to the development of attenuated total reflection/FUV spectroscopy. As other examples, DUV surfa…
This book addresses the differentiation control of skeletal muscle in different locations of the vertebrate body Particular attention is paid to novel regulatory molecules and signals as well as the heterogeneity of origin that have revealed a developmental overlap between skeletal and cardiac muscle. Different functional muscle groups are the product of the evolution of the vertebrate classes,…
This work addresses dynamical aspects of quantum criticality in two space dimensions. It probes two energy scales: the amplitude (Higgs) mode, which describes fluctuations of the order parameter amplitude in the broken symmetry phase, and the dual vortex superfluid stiffness. The results demonstrate that the amplitude mode can be probed arbitrarily close to criticality in the universal lineshap…
Physiology is the study of organ function and interaction. Physiology may be studied from the molecular level to the organism level. The hierarchical levels of organization of the human body from the smallest structure to the largest structure are molecular, cellular, tissue, organ system, and organism