The four sections of this book cover cell and molecular biology of tumor metabolism, metabolites, tumor microenvironment, diagnostics and epigenetics. Written by international experts, it provides a thorough insight into and understanding of tumor cell metabolism and its role in tumor biology. The book is intended for scientists in cancer cell and molecular biology, scientists in drug and diagn…
What should you do when you have restricted resources? Written by the most prominent experts from the North and the South countries, this book offers a unique complement to classical hematology and oncology textbooks focusing on specific issues concerning cancers in tropical areas. It presents a thorough review of the specific biological, clinical and therapeutic characteristics of cancers in t…
This monograph summarizes state of the art knowledge regarding peritoneal surface malignancies, with in-depth description of treatment options and the results achieved to date. It explores the most challenging problems on the basis of the authors’ very extensive clinical experience and examines the most relevant clinical trials. A comprehensive summary is provided of all phase 2 studies (the …
The field of colorectal surgery has undergone tremendous developments in recent decades. Surgery has become less invasive, new perspectives and insights have improved perioperative management and novel outcome measures have been defined. At the same time, the limits of surgical technique and perioperative care are being challenged by more complex patients. In order to realize the immense potent…
Based on 30 years of clinical and research experience, backed by a careful assessment of four decades of published data, Dr. Faguet documented in The War on Cancer (Springer 2005), early advances in cancer treatment and patient survival that soon stalled. Ten years later and after an exhaustive analysis of evidence-based data available through 2013 that incorporates 755 references, he reveals t…
A Case-Based Approach to PET/CT in Oncology describes the role of PET/CT in the diagnosis, staging and monitoring of treatment response in today's practice of oncology. It provides a detailed analysis of over 100 cases occurring in daily clinical practice, emphasizing the central role that PET imaging plays in the care of cancer patients. The text is organized into two sections; Part I guides t…
This richly illustrated volume describes the performance of total and subtotal gastrectomy with extended D2 lymphadenectomy by providing a detailed step-by-step guide to both manual and mechanical procedures. Gastric cancer is the fourth most commonly occurring cancer and the second most common cancer-related cause of death worldwide, and surgery remains the only potentially curative treatment.…
This book covers the entire spectrum of thyroid diseases in childhood, focusing on the recent advances that have been achieved, from progress in basic science research through to novel or improved approaches to diagnosis and treatment. Introductory chapters discuss thyroid embryogenesis and the role of thyroid hormones in fetal development. The two contrasting forms of thyroid dysfunction, hypo…
This book provides a 2015 state of the art update on the hot topic of focal prostate cancer therapy, which offers a means of preserving the prostate and avoiding major side-effects associated with conventional treatment strategies. In so doing, focal therapy meets the desire of many patients, especially those with low-risk disease, to avoid or postpone radical therapies in order to preserve qua…
This text presents the experiences of leading researchers and surgeons with different fluorescence methods. Chapters range from basic science of fluorescence to current clinical applications and new horizons. The first few chapters describe the historical evolution and physical principles of fluorescence and provide the foundation for the reader to understand the current scope and limits of its…