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New Approaches to Drug Discovery
This volume gives an overview of state of the art technologies and future developments in the field of preclinical pharmaceutical research. A balanced mix of experts from academia and industry give insight in selected new developments in the drug discovery pathway. The topics cover the different parts of the drug discovery process, starting with new developments in the target identification and…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-80455-2
- Collation
- VIII, 341
- Series Title
- Handbook of Experimental Pharmacology
- Call Number
- -
Lyophilized Biologics and Vaccines: Modality-Based Approaches
This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.g., monoclonal, fused), complex biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly guide…
- Edition
- -
- ISBN/ISSN
- 978-1-4939-2383-0
- Collation
- -
- Series Title
- -
- Call Number
- -
Metabonomics and Gut Microbiota in Nutrition and Disease
This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also …
- Edition
- -
- ISBN/ISSN
- 978-1-4471-6538-5
- Collation
- XVI, 375
- Series Title
- Molecular and Integrative Toxicology
- Call Number
- -
Metabolic Control
Stephan Herzig obtained his PhD from the University of Göttingen, Germany, in 1999. Supported by the German Research Foundation DFG he then joined the Salk Institute for Biological Studies, La Jolla, CA, for his postdoctoral training. In 2004, he established an Emmy-Noether and Marie Curie Junior Research Group at the German Cancer Research Center (DKFZ) in Heidelberg, Germany. He became Head …
- Edition
- 1
- ISBN/ISSN
- 978-3-319-29804-7
- Collation
- VIII, 469
- Series Title
- -
- Call Number
- -
Vaccine Analysis: Strategies, Principles, and Control
This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; co…
- Edition
- -
- ISBN/ISSN
- 978-3-662-45024-6
- Collation
- XII, 665
- Series Title
- -
- Call Number
- -
Biological Toxins and Bioterrorism
Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of …
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- 615.4
Biological Effects of Metal Nanoparticles
This book offers a comprehensive overview of recent studies conducted on the biological effects of metal nanoparticles. It also provides a solid theoretical foundation and various metal nanoparticle synthesis methods. Part I reviews the main chemical methods used for synthesizing metal nanoparticles in a solution and describes original method of biochemical synthesis, as well as some special…
- Edition
- -
- ISBN/ISSN
- 978-3-319-30906-4
- Collation
- -
- Series Title
- -
- Call Number
- 615.4
Tryptophan Metabolism: Implications for Biological Processes, Health and Disease
This book discusses the relationship between cellular immunity and tryptophan metabolism, as well as its products, serotonin and melatonin, in the development of several diseases and reappraises the common signal transduction pathways of the neurodegenerative diseases, carcinogenesis, immune tolerance, inflammation, hypersensitivity reactions, neuropsychiatric disorders, in addition to bacteria…
- Edition
- -
- ISBN/ISSN
- 978-3-319-15630-9
- Collation
- 4 b/w illustrations, 17 illustrations in colour
- Series Title
- -
- Call Number
- -
The Emerging Discipline of Quantitative Systems Pharmacology
In 2011, the National Institutes of Health (NIH), in collaboration with leaders from the pharmaceutical industry and the academic community, published a white paper describing the emerging discipline of Quantitative Systems Pharmacology (QSP), and recommended the establishment of NIH-supported interdisciplinary research and training programs for QSP. QSP is still in its infancy, but has tremend…
- Edition
- -
- ISBN/ISSN
- -
- Collation
- -
- Series Title
- -
- Call Number
- 615 LEI e
Advances in Cancer Biomarkers: From biochemistry to clinic for a critical rev…
At present there are a growing number of biomolecules under investigation to understand their potential role as cancer biomarker for diagnostic, prognostic and therapeutic purposes. Intriguingly, the state of art on cancer biomarkers research shows interesting and promising results together to clamorous failures. Also from a clinical point of view, there are contradictory results on routine cl…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-94-017-7215-0
- Collation
- IX, 372
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- 616.994 ADV a
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