This book brings together the most up-to-date information on recent research results of leading laboratories on aging science in East Asia, particularly in Japan, Korea, and Hong Kong. Starting with a comprehensive overview of various hypotheses on biological mechanisms of aging by Dr. Sataro Goto, each chapter covers broad aspects of the most recent findings in aging-related topics: centenaria…
The latest in a series of books from the International Hypoxia Symposia, this volume spans reviews on key topics in hypoxia, and abstracts from poster and oral presentations. The biannual International Hypoxia Symposia are dedicated to hosting the best basic scientific and clinical minds to focus on the integrative and translational biology of hypoxia. Long before ‘translational medicine’ w…
The purpose of this comprehensive text is to increase awareness of human reproduction and its consequences. The central theme links reproductive capacity, the social consequences of the multiple stresses this places on the environment and the ways this relates back to the reproductive health of humans and other animals. In the first section, the biology of human reproduction is discussed, inclu…
Over the past few decades technological advances in transcriptomics, proteomics, metabolomics, and glycomics along with the ability to selectively knockout genes of interest has greatly advanced our understanding of maternal-conceptus interactions that are essential for the establishment and maintenance of a successful pregnancy. This knowledge provides a foundation from which to build research…
This book examines how post-transcriptional mechanisms control endocrine function. This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones. The impacts of these mechanisms o…
This book focuses on the taxonomic diversity of the genus Tuber as economically important truffles. In contributions by internationally respected scientists, it examines truffle systematics, interactions with abiotic and biotic environments, strategies for spore dispersal, and molecular processes in truffles. Topics discussed include: evolutionary theories and phylogeny of Tuber species from As…
This book presents the latest information on tropical tree physiology, making it a valuable research tool for a wide variety of researchers. It is also of general interest to ecologists (e.g. Ecological Society of America; > 3000 or 4000 members at annual meeting), physiologists (e.g. American Society of Plant Biologists; > 2,000 members at annual meeting), and tropical biologists (e.g. Associa…
This book presents the state of the art of type 2 diabetes genetics, from the process of genetic discovery to its interpretation and clinical application, and illustrates a model for other complex human phenotypes. The first section explores genome-wide association studies, the extension of this method to less accessible phenotypes and the arrival of next-generation sequencing. A further secti…
E.F.F. Chladni’s experiments and observations with sound and vibrations profoundly influenced the development of the field of Acoustics. The famous Chladni diagrams along with other observations are contained in Die Akustik, published in German in 1802 and Traité d’Acoustique, a greatly expanded version, published in French in 1809. This is the first comprehensive translation of the expand…
This book provides a comprehensive review of the latest advances in translational pain and itch research, and presents the cutting-edge developments in the study of our two principal, yet most mysteries sensations. Despite the slow progress in the discovery of effective therapies for chronic pain and pruritus, scientists around the globe now have a better understanding of why and how these cond…