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Vascular Ion Channels in Physiology and Disease
Ion channels are the major class of membrane proteins responsible for rapid and regulated transport of ions across biological membranes and for the generation and propagation of electrical signals in the brain, heart, and skeletal and vascular tissues. Ion channels are also known to play critical roles in regulation of cell proliferation, insulin secretion and intracellular signaling in a varie…
- Edition
- -
- ISBN/ISSN
- 978-3-319-29635-7
- Collation
- XVII, 431
- Series Title
- -
- Call Number
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Agricultural Proteomics Volume 2: Environmental Stresses
This book will cover several topics to elaborate how proteomics may contribute in our understanding of mechanisms involved in stress adaptation. The knowledge being accumulated by a wide range of proteomics technologies may eventually be utilized in breeding programs to enhance stress tolerance. This book presents comprehensive reviews about responses of crop and farm animals to environmental s…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-319-43278-6
- Collation
- XI, 314
- Series Title
- -
- Call Number
- 630 AGR a
Agricultural Proteomics Volume 1: Crops, Horticulture, Farm Animals, Food, In…
This book will cover several topics to elaborate how proteomics may enhance agricultural productivity. These include crop and food proteomics, farm animal proteomics, aquaculture, microorganisms and insect proteomics. It will also cover several technical advances, which may address the current need for comprehensive proteome analysis.An emerging field of the proteomics aim is to integrate kno…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-319-43275-5
- Collation
- XI, 255
- Series Title
- -
- Call Number
- 630 AGR a
Urine Proteomics in Kidney Disease Biomarker Discovery
This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the…
- Edition
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- ISBN/ISSN
- 978-94-017-9523-4
- Collation
- 15 b/w illustrations, 10 illustrations in colour
- Series Title
- -
- Call Number
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Ubiquitin Chains: Degradation and Beyond
About this book This thesis examines the evidence for regulatory ubiquitination by focusing on A20. It provides an insightful and in-depth evaluation of the current literature by critically examining the evidence of K63-linked regulatory ubiquitination in regulating cell-signalling. It is also the first thesis to directly test the role of regulatory ubiquitination in NF-kB signaling in vivo. T…
- Edition
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- ISBN/ISSN
- 978-3-319-14965-3
- Collation
- 12 b/w illustrations, 33 illustrations in colour
- Series Title
- -
- Call Number
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Host Defense Peptides and Their Potential as Therapeutic Agents
This book offers an overview of our current understanding of host defense peptides and their potential for clinical applications as well as some of the obstacles to this. The chapters, written by leading experts in the field, detail the number and diversity of host defense peptides, and discuss the therapeutic potential not only of antibacterial, but also of antifungal, antiviral, plant antimic…
- Edition
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- ISBN/ISSN
- 978-3-319-32947-5
- Collation
- X, 321
- Series Title
- -
- Call Number
- 540 HOS
Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry
This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new me…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-319-35801-7
- Collation
- XI, 286
- Series Title
- -
- Call Number
- 574.192 ADV a
High Density Lipoproteins : From Biological Understanding To Clinical Exploit…
In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attemp…
- Edition
- -
- ISBN/ISSN
- 9783319230955
- Collation
- XIII, 694 halaman
- Series Title
- -
- Call Number
- 572.6 HIG
Advanced Technologies for Protein Complex Production and Characterization
This book presents advanced expression technologies for the production of protein complexes. Since complexes lie at the heart of modern biology, the expression, purification, and characterization of large amounts of high-quality protein complexes is crucial for the fields of biomedicine, biotechnology, and structural biology. From co-expression in E. coli, yeast, mammalian and insect cells to c…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-319-27216-0
- Collation
- XIII, 382
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- 574.75 ADV a
Large-Scale Quantum-Mechanical Enzymology
This work establishes linear-scaling density-functional theory (DFT) as a powerful tool for understanding enzyme catalysis, one that can complement quantum mechanics/molecular mechanics (QM/MM) and molecular dynamics simulations. The thesis reviews benchmark studies demonstrating techniques capable of simulating entire enzymes at the ab initio quantum-mechanical level of accuracy. DFT has trans…
- Edition
- -
- ISBN/ISSN
- 978-3-319-19351-9
- Collation
- -
- Series Title
- -
- Call Number
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