This book reviews current knowledge of the etiopathogenesis, pathophysiology, and molecular biology of tympanic membrane retraction pockets and provides clear guidance on clinical assessment and treatment. A new diagnostic approach based on clinicoradiologic correlations is presented, and the ability of computer tomography to offer objective criteria for improved differentiation between stable …
Esophageal cancer causes an estimated 386,000 deaths worldwide and is the sixth most common cause of death for men. The background characteristics of esophageal cancer treatment are markedly different between Asian and Western countries, however. In tumor histology, squamous cell carcinoma associated with smoking and alcohol consumption is overwhelmingly prevalent in Asia, whereas adenocarcinom…
This monograph summarizes state of the art knowledge regarding peritoneal surface malignancies, with in-depth description of treatment options and the results achieved to date. It explores the most challenging problems on the basis of the authors’ very extensive clinical experience and examines the most relevant clinical trials. A comprehensive summary is provided of all phase 2 studies (the …
This illustrated textbook is an essential and invaluable guide to young clinicians and researchers of Trauma and Orthopaedics, reporting all classification systems which are currently utilised in the clinical setting. It includes classifications relevant to both Elective Orthopaedic Practice and Orthopaedic Trauma. Clear graphic illustrations accompany the description of all different classi…
This book provides an up-to-date and comprehensive overview of the etiology, diagnosis and treatment of conditions affecting the structure and function of the right heart, comprising the right atrium, right ventricle, tricuspid valve and pulmonary circulation. Anatomy and physiology of the right heart, etiology and role of imaging of right heart failure, as well as treatment options, from pharm…
Due to a high incidence of anemia, critically ill patients are frequently transfused, with up to 40% of patients receiving a transfusion during their stay in the Intensive Care Unit. It has become increasingly clear that there is an association between transfusion and adverse outcomes, underlining the need for a careful assessment of the risks and benefits of a blood transfusion. In the last de…
The field of colorectal surgery has undergone tremendous developments in recent decades. Surgery has become less invasive, new perspectives and insights have improved perioperative management and novel outcome measures have been defined. At the same time, the limits of surgical technique and perioperative care are being challenged by more complex patients. In order to realize the immense potent…
This book provides the reader with an understanding of human nutritional and metabolic physiology and how it goes wrong in illness. Divided into three major sections, the volume instructs the reader on how and when to use nutritional support, and includes a summary of the published outcome studies on the application of nutritional support to the management of common illnesses. In this way, the …
This book provides a broad overview on training in Minimal Access Surgery, with expert opinions from leaders in the field clarifying the definitions and terminology related to competence and accreditation. It also provides expert advice on how to set up a training unit and explores the role and impact of all types of simulations on training including virtual reality simulation. How to design a …
Cell Therapy for Brain Injury is a thorough examination of using state-of-the-art cell therapy in the treatment of strokes and other traumatic brain injuries. This invaluable book covers this niche topic in depth from basic stem cell biology and principles of cell therapy through proposed mechanisms of action of cell therapy in stroke, pre-clinical data in stroke models, ongoing clinical trials…