This book discusses the different regulatory pathways for gene therapy (GT) and cell therapy (CT) medicinal products implemented by national and international bodies throughout the world (e.g. North and South America, Europe, and Asia). Each chapter, authored by experts from various regulatory bodies throughout the international community, walks the reader through the applications of nonclinica…
This is a no-nonsense guide to drug treatment in the intensive care unit. It covers the most commonly encountered conditions and is organized by system. Management of each condition is tersely outlined step-by-step in table format. The book also includes non-drug information that is essential to making informed, evidence-based pharmacotherapy decisions, such as risk scores, scales, and asses…
This Pocket Reference offer a multifaceted guide on various aspects of Alzheimer’s disease. This thorough review discusses the challenges of diagnosis, different stages of the disease, testing, and current treatment methods, including pharmacological and nonpharmacological management of cognitive decline and symptoms due to Alzheimer’s disease. The book also has specific chapters on care is…
Critics of narcology—as addiction medicine is called in Russia—decry it as being "backward," hopelessly behind contemporary global medical practices in relation to addiction and substance abuse, and assume that its practitioners lack both professionalism and expertise. On the basis of his research in a range of clinical institutions managing substance abuse in St. Petersburg, Eugene Raikhel…
Esophageal cancer causes an estimated 386,000 deaths worldwide and is the sixth most common cause of death for men. The background characteristics of esophageal cancer treatment are markedly different between Asian and Western countries, however. In tumor histology, squamous cell carcinoma associated with smoking and alcohol consumption is overwhelmingly prevalent in Asia, whereas adenocarcinom…
What should you do when you have restricted resources? Written by the most prominent experts from the North and the South countries, this book offers a unique complement to classical hematology and oncology textbooks focusing on specific issues concerning cancers in tropical areas. It presents a thorough review of the specific biological, clinical and therapeutic characteristics of cancers in t…
This monograph summarizes state of the art knowledge regarding peritoneal surface malignancies, with in-depth description of treatment options and the results achieved to date. It explores the most challenging problems on the basis of the authors’ very extensive clinical experience and examines the most relevant clinical trials. A comprehensive summary is provided of all phase 2 studies (the …
A new take on therapeutic mindfulness with specific applications to troubled and delinquent youth is the focus of this innovative text. It introduces Family Mode Deactivation Therapy (FMDT) and its core concepts and methodologies, differentiating it from other cognitive and mindfulness therapies for adolescents with problem behaviors and comorbid conditions. Step by step applications of FMDT fr…
This book provides an overview of recent trends in the management of trauma and post-traumatic stress disorders that may ensue from distressing experiences associated with the process of migration. Although the symptoms induced by trauma are common to all cultures, their specific meaning and the strategies used to deal with them may be culture-specific. Consequently, cultural factors can play a…
N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced. Whet…