Provides a comprehensive overview and introduction to the concepts, methodologies, analysis, design and applications of metasynthetic computing and engineering. The author: • Presents an overview of complex systems, especially open complex giant systems such as the Internet, complex behavioural and social problems, and actionable knowledge discovery and delivery in the big data era. • Discu…
This book provides a unified overview of network-on-chip router micro-architecture, the corresponding design opportunities and challenges, and existing solutions to overcome these challenges. The discussion focuses on the heart of a NoC, the NoC router, and how it interacts with the rest of the system. Coverage includes both basic and advanced design techniques that cover the entire router desi…
The book describes how plant biomass can be used as renewable feedstock for producing and further processing various products. Particular attention is given to microbial processes both for the digestion of biomass and the synthesis of platform chemicals, biofuels and secondary products. Topics covered include: new metabolic pathways of microbes living on green plants and in silage; using lig…
This book explores the nature of pregnancy and metabolic syndrome as proinflammatory conditions and explains how pregnancy provides a window of opportunity for preventing the lifelong complications of metabolic syndrome, during which key risk factors can be identified and beneficial dietary changes can be implemented. The book’s opening sections discuss inflammation in the context of pregn…
Stephan Herzig obtained his PhD from the University of Göttingen, Germany, in 1999. Supported by the German Research Foundation DFG he then joined the Salk Institute for Biological Studies, La Jolla, CA, for his postdoctoral training. In 2004, he established an Emmy-Noether and Marie Curie Junior Research Group at the German Cancer Research Center (DKFZ) in Heidelberg, Germany. He became Head …
This essential volume explores mesenchymal stem cells (MSCs) and their potential to suppress immune-mediated inflammation. The chapters examine applications in autoimmune diseases such as lupus, rheumatoid arthritis and multiple sclerosis; blood cancers such as leukemia and lymphoma; and reproductive complications, specifically pre-term labor and use of MSCs in vitro and in animal models to dis…
This book discusses the design and performance analysis of SDRAM controllers that cater to both real-time and best-effort applications, i.e. mixed-time-criticality memory controllers. The authors describe the state of the art, and then focus on an architecture template for reconfigurable memory controllers that addresses effectively the quickly evolving set of SDRAM standards, in terms of worst…
This book explores the microsensing technologies and systems now available to monitor the quality of air and water within the urban environment and examines their role in the creation of sustainable cities against the background of the challenges posed by rapid urbanization. The opening section addresses the theoretical and conceptual background of microsensing networks. The coverage includes d…
With a focus on food safety, this book highlights the importance of microbes in sustainable agriculture. Plants, sessile organisms that are considered as primary producers in the ecosystem and communicate with above- and below-ground communities that consist of microbes, insects, and other vertebrate and invertebrate animals, are subjected to various kinds of stress. Broadly speaking, these can…
This book reviews the mechanisms, patterns, and processes that regulate prokaryotic diversity through different habitats in the context of evolutionary and ecological hypotheses, principles, and theories. Despite the tremendous role of prokaryotic diversity in the function of the global ecosystem, it remains understudied in comparison to the rest of biological diversity. In this book, the autho…