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Genome Editing
This comprehensive volume explores human genetic engineering its pre-clinical and clinical applications, current developments, and as treatment for hereditary diseases. It presents and evaluates the most recent advances in the understanding of mammalian host DNA repair mechanisms, such as double-strand break induced gene targeting and mutagenesis, the development of zinc-finger nucleases, genom…
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- ISBN/ISSN
- 978-1-4939-3507-9
- Collation
- XVI, 263
- Series Title
- -
- Call Number
- 363.92 GEN
Studies on Hepatic Disorders
This volume examines the current state of free radical biology as it impacts on hepatic disorders. It takes a thorough look at the relationship of oxidative stress in acute and chronic disease and takes into account factors like: redox biomarkers; antioxidant defense and protection; cell signaling, mutations; oxidative damage involving lipids, proteins and nucleic acids; membrane trafficking, i…
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- ISBN/ISSN
- 978-3-319-15539-5
- Collation
- XXII, 516
- Series Title
- Oxidative Stress in Applied Basic Research and Clinical Practice
- Call Number
- -
Studies on Experimental Toxicology and Pharmacology
This book focuses on data describing the roles of free radicals and related reactive species, and antioxidants, in the causes and treatments of diseases, examining both clinical and pre-clinical trials, as well as basic research. The book is divided into sub-sections with chapters on toxicological mechanisms, agents that produce toxicity, and special topics including areas such as antioxidant s…
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- ISBN/ISSN
- 978-3-319-19096-9
- Collation
- XVI, 498
- Series Title
- Oxidative Stress in Applied Basic Research and Clinical Practice
- Call Number
- -
Genetics of Melanoma
This book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge …
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- ISBN/ISSN
- 978-1-4939-3552-9
- Collation
- XV, 288
- Series Title
- -
- Call Number
- 616 Gen
Intracellular Delivery III: Market Entry Barriers of Nanomedicines
A critical review is attempted to assess the status of nanomedicine entry onto the market. The emergence of new potential therapeutic entities such as DNA and RNA fragments requires that these new “drugs” will need to be delivered in a cell-and organelle-specific manner. Although efforts have been made over the last 50 years or so to develop such delivery technology, no effective and above …
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- ISBN/ISSN
- 978-3-319-43525-1
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- -
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Intestinal Tumorigenesis: Mechanisms of Development & Progression
This volume includes the information necessary to understand recent critical advances in the mechanisms of intestinal tumorigenesis and to comprehend the complexity of the process. The volume aims to entice new researchers to participate in relevant studies, and to provide a forum for discussion within the scientific community to shape future research in this field. Discoveries in intestinal tu…
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- ISBN/ISSN
- 978-3-319-19986-3
- Collation
- -
- Series Title
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Structure-Based Mechanics of Tissues and Organs
This book portrays the commonality of tissue micro-structure that dictates physiological function in various organs (microstructure-function relation). Tissue and organ models are used to illustrate physiological functions based on microstructure. Fiber scale properties such as orientation and crimp are described in detail. Structurally-based constitutive models are given throughout the book, n…
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- ISBN/ISSN
- 978-1-4899-7630-7
- Collation
- XXXIV, 469
- Series Title
- -
- Call Number
- -
Structure and Function of Mountain Ecosystems in Japan
The purpose of this book is to summarize new insights on the structure and function of mountain ecosystems and to present evidence and perspectives on the impact of climate change on biodiversity. This volume describes overall features of high-mountain ecosystems in Japan, which are characterized by clear seasonality and snow-thawing dynamics. Individual chapters cover a variety of unique topic…
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- ISBN/ISSN
- 978-4-431-55954-2
- Collation
- VII, 173
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- -
- Call Number
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Internet Addiction: Neuroscientific Approaches and Therapeutical Interventions
This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by…
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- ISBN/ISSN
- 978-3-319-07242-5
- Collation
- -
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Raynaud’s Phenomenon: A Guide to Pathogenesis and Treatment
Raynaud’s Phenomenon: A Guide to Pathogenesis and Treatment comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists alike. In the last decade, there have been important advances not only in understanding the pathophysiology of Raynaud’s Phenomenon (RP), but also in developing diagnostic methods and effective drug and non-dr…
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- ISBN/ISSN
- 978-1-4939-1526-2
- Collation
- -
- Series Title
- -
- Call Number
- 616.5
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