This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and statistical tools for translational bioinformatics in the areas of gene transcription and regulatio…
Nearly 30 years ago, a number of scientists working on the Enteric Nervous System (ENS) gathered at Flinders University, in Adelaide, Australia to discuss the advances and future of their research. It was a friendly and stimulating meeting, attended by most of the major players, in what was to become the discipline of ‘Neurogastroenterology'. In 2014, the main Australasian Neuroscience Soc…
The meeting of Aquatic Noise 2013 will introduce participants to the most recent research data, regulatory issues and thinking about effects of man-made noise and will foster critical cross-disciplinary discussion between the participants. Emphasis will be on the cross-fertilization of ideas and findings across species and noise sources. As with its predecessor, The Effects of Noise on Aquatic …
This monograph explores the early development of the calculus of variations in continental Europe during the Eighteenth Century by illustrating the mathematics of its founders. Closely following the original papers and correspondences of Euler, Lagrange, the Bernoullis, and others, the reader is immersed in the challenge of theory building. We see what the founders were doing, the difficulties …
This book describes a new computational approach to creativity. With chess as the domain of investigation, the authors show experimentally how a computer can be imbued with the 'spark' of creativity that enables it to compose chess problems or puzzles that are both challenging and aesthetically appealing to humans. This new approach called the Digital Synaptic Neural Substrate (DSNS) mimics the…
On 4 June 1629, the Batavia, pride of the Dutch East India Company Fleet, was wrecked on her maiden voyage in a seemingly empty expanse of the Indian Ocean. The question “how did this happen?” led to 300 years of investigation by those curious to solve the enigma: what are corals and how are coral reefs formed?. Relying heavily on primary source material Part 1 traces the sequential evol…
This book presents new insights into Leibniz’s research on planetary theory and his system of pre-established harmony. Although some aspects of this theory have been explored in the literature, others are less well known. In particular, the book offers new contributions on the connection between the planetary theory and the theory of gravitation. It also provides an in-depth discussion of Kep…
This volume details the essential role of the spiral ganglion neurons. The volume elucidates and characterizes their development, their environment, their electrophysiological characteristics, their connectivity to their targets in the inner ear and the brain, and discusses the potential for their regeneration. A comprehensive review about the spiral ganglion neurons is important for researcher…
Provides a comprehensive summary on the physical models and current theory of black hole accretion, growth and mergers, in both the supermassive and stellar-mass cases. This title reviews in-depth research on accretion on all scales, from galactic binaries to intermediate mass and supermassive black holes. Possible future directions of accretion are also discussed. The following main themes …
This is the first book solely devoted to Cryopedology, the study of soils of cold regions. The analysis treats Cryosols as a three-part system (active layer, transition layer, permafrost). The book considers soil-forming factors, cryogenic processes, and classification and distribution of Cryosols. Cryosols of the Arctic, Antarctica, and the high mountains are considered in detail. The chapters…