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Evolutionary Bioinformatics
Now in its third edition and supplemented with more online material, this book aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people. Books on bioinformatics have traditionally served gene-hunters, and biologists who wish to construct family trees showing tidy lines of descent. While dealing extensively with …
- Edition
- -
- ISBN/ISSN
- 978-3-319-28755-3
- Collation
- 92 b/w illustrations, 24 illustrations in colour
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Evolution of the Protein Synthesis Machinery and Its Regulation
The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.
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- ISBN/ISSN
- 978-3-319-39468-8
- Collation
- Springer International
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Multifaceted Roles of Crystallography in Modern Drug Discovery
The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug d…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-9718-4
- Collation
- XI, 240
- Series Title
- NATO Science for Peace and Security Series A: Chemistry and Biology
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Modern Proteomics – Sample Preparation, Analysis and Practical Applications
This volume serves as a proteomics reference manual, describing experimental design and execution. The book also shows a large number of examples as to what can be achieved using proteomics techniques. As a relatively young area of scientific research, the breadth and depth of the current state of the art in proteomics might not be obvious to all potential users. There are various books and rev…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-41446-1
- Collation
- IX
- Series Title
- Advances in Experimental Medicine and Biology
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Molecular Pathology in Cancer Research
The aim of the book is to discuss the application of molecular pathology in cancer research, and its contribution in the classification of different tumors and identification of potential molecular targets, as well as how this knowledge may be translated into clinical practice, and the huge impact this field is likely to have in the next 5 to 10 years.
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-6641-7
- Collation
- VIII, 369
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- Call Number
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Kinesins and Cancer
This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting the importance of kinesins, summarising current knowledge and how they are shown to be crucial for mitosis. Chapters go on to explore how this family of protei…
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- ISBN/ISSN
- 978-94-017-9732-0
- Collation
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Membrane Protein – Lipid Interactions: Physics and Chemistry in the Bilayer
This book has been conceives as a brief introduction to biomembranes physical chemistry for undergraduate students of sciences, and it is particularly dedicated to the lipid-protein membrane interactions. A general introduction is presented in Chapters 1 and 2. The following Chapters, 3 and 4, describe the most accepted theories on lipid-membrane protein interactions as well as the new experime…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-30275-1
- Collation
- XIV, 116
- Series Title
- Membrane Protein – Lipid Interactions: Physics and Chemistry in the Bilayer
- Call Number
- -
Ion Channels and Transporters of Epithelia in Health and Disease
This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and tran…
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- ISBN/ISSN
- 978-1-4939-3366-2
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- -
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ADAMTS13: Biology and Disease
This comprehensive volume discusses the protease ADAMTS13, summarizing the current status of basic and clinical research. The nine authoritative chapters begin with a historical perspective followed by exploration of the biochemistry and structure-function relationships of ADAMTS13 as well as its normal function in hemostasis (cleavage of von Willebrand factor). Emerging research themes for ADA…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-319-08717-7
- Collation
- X, 186
- Series Title
- -
- Call Number
- 574.192 ADA a
Intrinsically Disordered Proteins Studied by NMR Spectroscopy
This book discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). The properties of IDPs and IDPRs are highly complementary to those deriving from the presence of a unique and well-defined three-dimensional fold. Ignored for a long time in high-resolution studies of proteins, intrin…
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- ISBN/ISSN
- 978-3-319-20164-1
- Collation
- -
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