The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin …
This book serves as a comprehensive introductory guide to the practical aspects of risk assessment. Chapters include clearly defined objectives and summaries. The book includes: hazard identification, dose-response, exposure assessment, risk characterization, chemical mixtures, epidemiology, emerging issues and global perspectives with accessible language. The book concludes with a set of hypot…
This powerful resource identifies wide-scale health challenges facing a rapidly urbanizing planet--including key concerns in nutrition, health status, health care, and safety--and strategies toward possible solutions. Theoretical and empirical analysis focuses on maximizing the benefits of urban living and minimizing negative outcomes across areas for improvement (health education, maternal and…
This briefs integrates and synthesizes an array of research about who helps others and under what conditions and discusses the implications of this research for a bystander intervention focused prevention agenda to reduce sexual and relationship violence in schools and communities. It combines an examination of bystander helping behavior in the specific context of sexual and relationship violen…
This book offers a comprehensive guide to total knee arthroplasty (TKA) that will assist in achieving excellent outcomes based on a sound understanding and technique. After an introductory section on the native knee that covers the anatomy, physiology, biomechanics, and patterns of disease, all aspects of primary knee arthroplasty are discussed in detail. Individual chapters are devoted to topi…
This direct, accessible guide uses a human rights perspective to define effectiveness in aid delivery and offer a robust framework for creating sustainable health programs and projects and assessing their progress. Geared toward hands-on professionals in such critical areas as food aid, maternal health, and disease control, it lays out challenges and solutions related to funding, planning, and …
This book helps in Achieving food safety success which requires going beyond traditional training, testing, and inspectional approaches to managing risks. It requires a better understanding of the human dimensions of food safety. In the field of food safety today, much is documented about specific microbes, time/temperature processes, post-process contamination, and HACCP–things often called …
This book explores the links between food and democracy. It addresses how democratic principles can be used to shape our food system and takes a practical ‘how-to’ approach to using democratic processes to regain control of the food we eat. It also highlights what food democracy looks like on the ground and how individuals, communities and societies can be empowered to access, cook and eat …
This book explores the unresolved paradox at the heart of population aging, namely how to account for the fact that death rates from most non-communicable diseases rise as people age, yet aggregate death rates from such diseases have decreased overall despite an increasingly aging population. It provides a long-term historical perspective on this issue, presenting evidence that the underpinning…
This book looks at health policy through the lens of public versus private: population health versus the somatic, social, or emotional experiences of a patient. Rather than presenting policy/ethics as overly technical, this book takes a novel approach of framing public and private health in terms of political philosophy, ethics, and popular examples. Each chapter ties back to the general ethics…