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Molecular and Cellular Mechanobiology
This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological reg…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-5615-9
- Collation
- XIII, 302
- Series Title
- Physiology in Health and Disease
- Call Number
- -
Molecular and Cellular Biology of Platelet Formation
This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and r…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-39560-9
- Collation
- X, 460
- Series Title
- -
- Call Number
- -
Molecular Therapies of Cancer
Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the t…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-13277-8
- Collation
- XV, 488
- Series Title
- -
- Call Number
- -
Molecular Targets and Strategies in Cancer Prevention
The book focuses on the understanding of molecular pathways by which normal cell progress to the definable stage of cancer. The chapters explore microbiota and chronic inflammation, multiple myeloma chemoprevention, microRNAs, cancer regulation, liquid biopsies, and angiogenesis. Recent advances of molecular risk assessment, tumor microenvironment, microneoplasia, malignant gene expressions are…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-31252-1
- Collation
- V, 180
- Series Title
- -
- Call Number
- -
Molecular Structures and Structural Dynamics of Prion Proteins and Prions
This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased infectious prions (PrPSc), using MD and MM techniques. As we all know, prion diseases, caused by…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-7317-1
- Collation
- XIX, 355
- Series Title
- Focus on Structural Biology
- Call Number
- -
Morphomechanics of Development
This book outlines a unified theory of embryonic development, assuming morphogenesis to be a multi-level process including self-organizing steps while also obeying general laws. It is shown how molecular mechanisms generate mechanical forces, which in the long run lead to morphological changes. Questions such as how stress-mediated feedback acts at the cellular and supra-cellular levels and ho…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-35365-4
- Collation
- -
- Series Title
- -
- Call Number
- -
Morphogenesis and Individuation
This contributed volume aims to reconsider the concept of individuation, clarifying its articulation with respect to contemporary problems in perceptual, neural, developmental, semiotic and social morphogenesis. The authors approach the ontogenetical issue by taking into account the morphogenetic process, involving the concept of individuation proposed by Gilbert Simondon and Gilles Deleuze. Th…
- Edition
- 1
- ISBN/ISSN
- 2195-1934
- Collation
- -
- Series Title
- Lecture Notes in Morphogenesis
- Call Number
- -
Modeling the Heart and the Circulatory System
The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the fl…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-05229-8
- Collation
- XIV, 238
- Series Title
- MS&A
- Call Number
- -
The Th2 Type Immune Response in Health and Disease From Host Defense and All…
The type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified. It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL-13, is associated with helminth infections in both humans and mice. This response is co…
- Edition
- -
- ISBN/ISSN
- 978-1-4939-2911-5
- Collation
- -
- Series Title
- -
- Call Number
- -
Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics
The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body.The book is divided into four parts; the first deals with the fundamental principle…
- Edition
- 2
- ISBN/ISSN
- 978-3-319-27596-3
- Collation
- XXII, 483
- Series Title
- Interdisciplinary Applied Mathematics
- Call Number
- -
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