Long considered a "black art", designers of digital, analog, radio-frequency and mixed-signal systems are now looking to means for automating the design flow of electronic circuits using new, computationally intelligent approaches, based on modeling, synthesis, design methodologies, optimization algorithms, and metaheuristics. This book explains the application of recent advances in computation…
Le but du livre est de définir et développer une grande gamme d'outils probabilistes pour la modélisation en biologie des populations, afin de décrire des dynamiques temporelles de quantités biologiques telles que la taille d'une ou plusieurs populations, la proportion d'un allèle dans une population ou la position d'un individu. En partant de modèles markoviens discrets (marches alé…
This monograph presents new developments in multi-level decision-making theory, technique and method in both modeling and solution issues. It especially presents how a decision support system can support managers in reaching a solution to a multi-level decision problem in practice. This monograph combines decision theories, methods, algorithms and applications effectively. It discusses in de…
This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased infectious prions (PrPSc), using MD and MM techniques. As we all know, prion diseases, caused by…
The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the fl…
This book covers the latest advances in playful user interfaces – interfaces that invite social and physical interaction. These new developments include the use of audio, visual, tactile and physiological sensors to monitor, provide feedback and anticipate the behavior of human users. The decreasing cost of sensor and actuator technology makes it possible to integrate physical behavior inform…
The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body.The book is divided into four parts; the first deals with the fundamental principle…
This book presents the refereed proceedings of the Eleventh International Conference on Monte Carlo and Quasi-Monte Carlo Methods in Scientific Computing that was held at the University of Leuven (Belgium) in April 2014. These biennial conferences are major events for Monte Carlo and quasi-Monte Carlo researchers. The proceedings include articles based on invited lectures as well as carefully s…
This book covers the latest advances in Big Data technologies and provides the readers with a comprehensive review of the state-of-the-art in Big Data processing, analysis, analytics, and other related topics. It presents new models, algorithms, software solutions and methodologies, covering the full data cycle, from data gathering to their visualization and interaction, and includes a set of c…
This book is a unique reference work in the area of atomic-scale simulation of glasses. For the first time, a highly selected panel of about 20 researchers provides, in a single book, their views, methodologies and applications on the use of molecular dynamics as a tool to describe glassy materials. The book covers a wide range of systems covering "traditional" network glasses, such as chalcoge…