Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotecti…
Buku ini merupakan buku Physiology Question-Based Learning (PqBL) kedua dan merupakan kelanjutan dari buku PqBL pertama yang berisi tentang fisiologi sistem kardiovaskular, pernapasan, dan ginjal. Salah satu tema yang disoroti dalam buku kedua adalah aspek dinamis dari aliran darah, yaitu aliran darah, aliran udara, dan aliran cairan tubular. Buku PqBL kedua ini mencakup tiga sistem fisiologis …
This unifying theme of this book-with sections on mechanisms of defense and neuropathogenesis, neurological diseases, infections of the nervous system, neuropharmacology, and novel therapies-is interactions of the immune and nervous systems. It also discusses the role of inflammation as a key mediator of different brain disorders. There have been significant scientific advances in the multidisc…
The cerebrospinal fluid (CSF) is an invaluable diagnostic tool in clinical neurology, not only in the evaluation of inflammatory, degenerative, and malignant diseases of the nervous system, but also in the diagnosis of all forms of cerebral and subarachnoidal bleedings. The CSF can be easily obtained by lumbar puncture and a set of basic analyses can be conducted using relatively simple laborat…
Cerebral visual disorders have far-reaching consequences for child development. These have profound adverse effects on children’s education and success in school and also in later life, but, unfortunately, cerebral visual disorders often remain undiagnosed and untreated in the pediatric population. This book provides a state-of-the-art account of what is known about the development and disord…
This book demonstrates that the systematic study of gene expression patterns in embryonic and adult brains, in combination with selected data from earlier studies, can pave the way for a new neuromorphology, the most salient features of which may be summarized as follows: (1) Causal analysis of molecular patterning at neural plate and early neural tube stages has shown that the CNS is essential…
In this book, Hanadi Mubarak, Ali Husain and Michael promote the concept of innovation incubators from a business-management perspective. The book provides a comprehensive roadmap for the development of new economies based on technology, as well as value added in technology transfer, innovation development and an entrepreneurial climate. Many books on innovation and entrepreneurship take a t…
Cellular therapy for stroke and neural trauma has gained worldwide attention during the last decade and has shown some promising results. Various cells, including neural stem cells, bone marrow stem cells, endothelial progenitor cells, and many others have had protective or regenerative effects in animal models. The proposed book will address recent research on all relevant cell types. In addi…
Cell Therapy for Brain Injury is a thorough examination of using state-of-the-art cell therapy in the treatment of strokes and other traumatic brain injuries. This invaluable book covers this niche topic in depth from basic stem cell biology and principles of cell therapy through proposed mechanisms of action of cell therapy in stroke, pre-clinical data in stroke models, ongoing clinical trials…
This book provides the practicing physician with a practical approach to the diagnosis, evaluation and management of headache disorders based on lessons learned from real-life headache patients. Internationally well-known headache experts present cases from their own practice and discuss the evaluation and management of each case step by step. The clearly structured chapters cover initial evalu…