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Molecular Structures and Structural Dynamics of Prion Proteins and Prions
This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased infectious prions (PrPSc), using MD and MM techniques. As we all know, prion diseases, caused by…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-7317-1
- Collation
- XIX, 355
- Series Title
- Focus on Structural Biology
- Call Number
- -
Morphomechanics of Development
This book outlines a unified theory of embryonic development, assuming morphogenesis to be a multi-level process including self-organizing steps while also obeying general laws. It is shown how molecular mechanisms generate mechanical forces, which in the long run lead to morphological changes. Questions such as how stress-mediated feedback acts at the cellular and supra-cellular levels and ho…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-35365-4
- Collation
- -
- Series Title
- -
- Call Number
- -
Morphogenesis and Individuation
This contributed volume aims to reconsider the concept of individuation, clarifying its articulation with respect to contemporary problems in perceptual, neural, developmental, semiotic and social morphogenesis. The authors approach the ontogenetical issue by taking into account the morphogenetic process, involving the concept of individuation proposed by Gilbert Simondon and Gilles Deleuze. Th…
- Edition
- 1
- ISBN/ISSN
- 2195-1934
- Collation
- -
- Series Title
- Lecture Notes in Morphogenesis
- Call Number
- -
Modeling the Heart and the Circulatory System
The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the fl…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-05229-8
- Collation
- XIV, 238
- Series Title
- MS&A
- Call Number
- -
The Th2 Type Immune Response in Health and Disease From Host Defense and All…
The type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified. It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL-13, is associated with helminth infections in both humans and mice. This response is co…
- Edition
- -
- ISBN/ISSN
- 978-1-4939-2911-5
- Collation
- -
- Series Title
- -
- Call Number
- -
Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics
The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body.The book is divided into four parts; the first deals with the fundamental principle…
- Edition
- 2
- ISBN/ISSN
- 978-3-319-27596-3
- Collation
- XXII, 483
- Series Title
- Interdisciplinary Applied Mathematics
- Call Number
- -
Molecular Pathology of Breast Cancer
The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and cl…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-41759-2
- Collation
- VIII, 428
- Series Title
- -
- Call Number
- -
Molecular Pathology in Cancer Research
Cancer Biology, Medical Genetics, Cell Biology, Protein Biochemistry, Molecular Genetics
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-6641-7
- Collation
- VIII, 369
- Series Title
- -
- Call Number
- -
Molecular Parasitology
In the past years, genome projects for numerous human parasites have been completed and now allow first in depth comparisons and evolutionary conclusions. The genomes of parasites reflect the coevolution with their host, metabolic capacities depending on their respective habitat in the host. Gut parasites usually have an anaerobic metabolism, while blood parasites have an aerobic metabolism, in…
- Edition
- 1
- ISBN/ISSN
- 978-3-7091-1415-5
- Collation
- IX, 547
- Series Title
- -
- Call Number
- -
Molecular Mechanisms of Cell Differentiation in Gonad Development
This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of th…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-31971-1
- Collation
- XII, 434
- Series Title
- Results and Problems in Cell Differentiation
- Call Number
- -
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