This book is a collection of articles by leading researchers working at the cutting edge of neuro-computational modelling of neurological and psychiatric disorders. Each article contains model validation techniques used in the context of the specific problem being studied. Validation is essential for neuro-inspired computational models to become useful tools in the understanding and treatmen…
Many patients with pulmonary complaints fail to improve despite physicians’ best efforts. Sometimes, we ascribe this failure to lack of adherence with therapy, or to the severity of the condition. What we often fail to appreciate, however, is that sometimes the lack of improvement can be explained by the patients' psychological states. The first section of Functional Respiratory Disorders: W…
How did citizens in Bruges create a home? What did an ordinary domestic interior look like in the sixteenth century? And more importantly: how does one study the domestic culture of bygone times by analysing documents such as probate inventories? These questions seem straightforward, yet few endeavours are more challenging than reconstructing a sixteenth-century domestic reality from written so…
This atlas presents normal and pathologic findings observed on CT angiography with 3D reconstruction in a diverse range of clinical applications, including the imaging of cerebral, carotid, thoracic, coronary, abdominal and peripheral vessels. The superb illustrations display the excellent anatomic detail obtained with CT angiography and depict the precise location of affected structures and le…
This volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities. Topics include composition and quality control, toxicokinetics, interactions, safety pharmacology, approaches to studying complex mixtures including metabolomics and systems network pharmacology, and long-term toxicity. The volume also discusses vario…
This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respectiv…
Newcastle upon Tyne is one of England’s great cities. Many think of it mainly as a product of the Industrial Revolution when abundant resources of coal, iron ore and water came together to create a Victorian industrial powerhouse. In fact, Newcastle’s long and proud history began in Roman times when Hadrian’s Wall marked the northernmost point of the Roman Empire.Newcastle became a thrivi…
Spin glasses are magnetic materials with strong disorder. Statistical mechanics has been a powerful tool to theoretically analyse various unique properties of spin glasses. A number of new analytical techniques have been developed to establish a theory of spin glasses. Surprisingly, these techniques have offered new tools and viewpoints for the understanding of information processing problems, …
This open acess book extends recent work on entrepreneurship in response to adverse events to explore entrepreneurial responses by people who face chronic adversity more deeply. Instead of focusing on the sort of responses intended to destroy the institutions that create and sustain chronic adversity, the authors are interested in how individuals use entrepreneurial action to find a way within …