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Advanced Technologies for Protein Complex Production and Characterization
This book presents advanced expression technologies for the production of protein complexes. Since complexes lie at the heart of modern biology, the expression, purification, and characterization of large amounts of high-quality protein complexes is crucial for the fields of biomedicine, biotechnology, and structural biology. From co-expression in E. coli, yeast, mammalian and insect cells to c…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-319-27216-0
- Collation
- XIII, 382
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- 574.75 ADV a
Glycosignals in Cancer: Mechanisms of Malignant Phenotypes
This book is a collection of cutting-edge studies on the functions and mechanisms of glycosylation in cancers. Along with progress in genomics and proteomics, new findings in the significance of these complex carbohydrates, through the regulation of cell signals, have been elucidated in a wide variety of biological events. This volume provides a comprehensive summary of glycosignals and their i…
- Edition
- -
- ISBN/ISSN
- 978-4-431-55937-5
- Collation
- VIII, 219
- Series Title
- -
- Call Number
- 540.1 GLY
Advanced Polymers in Medicine
The book provides an up-to-date overview of the diverse medical applications of advanced polymers. The book opens by presenting important background information on polymer chemistry and physicochemical characterization of polymers. This serves as essential scientific support for the subsequent chapters, each of which is devoted to the applications of polymers in a particular medical specialty. …
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-319-12478-0
- Collation
- VIII, 537
- Series Title
- -
- Call Number
- 615.4 ADV a
Glycoscience: Biology and Medicine
The aim of the book is to provide a succinct overview of the current status of glycoscience from both basic biological and medical points of view and to propose future directions, in order to facilitate further integrations of glycoscience with other fields in biological and medical studies. Glycans (carbohydrate oligomers) are the so-called “building blocks” of carbohydrates, nucleic ac…
- Edition
- -
- ISBN/ISSN
- 978-4-431-54840-9
- Collation
- LXII, 1568
- Series Title
- -
- Call Number
- 572 GLY
Glucocorticoid Signaling: From Molecules to Mice to Man
This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the thi…
- Edition
- -
- ISBN/ISSN
- 978-1-4939-2894-1
- Collation
- XI, 385
- Series Title
- -
- Call Number
- 574.13 GLU
Large-Scale Quantum-Mechanical Enzymology
This work establishes linear-scaling density-functional theory (DFT) as a powerful tool for understanding enzyme catalysis, one that can complement quantum mechanics/molecular mechanics (QM/MM) and molecular dynamics simulations. The thesis reviews benchmark studies demonstrating techniques capable of simulating entire enzymes at the ab initio quantum-mechanical level of accuracy. DFT has trans…
- Edition
- -
- ISBN/ISSN
- 978-3-319-19351-9
- Collation
- -
- Series Title
- -
- Call Number
- -
Evolutionary Bioinformatics
Now in its third edition and supplemented with more online material, this book aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people. Books on bioinformatics have traditionally served gene-hunters, and biologists who wish to construct family trees showing tidy lines of descent. While dealing extensively with …
- Edition
- -
- ISBN/ISSN
- 978-3-319-28755-3
- Collation
- 92 b/w illustrations, 24 illustrations in colour
- Series Title
- -
- Call Number
- -
Evolution of the Protein Synthesis Machinery and Its Regulation
The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.
- Edition
- -
- ISBN/ISSN
- 978-3-319-39468-8
- Collation
- Springer International
- Series Title
- -
- Call Number
- -
Multifaceted Roles of Crystallography in Modern Drug Discovery
The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug d…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-9718-4
- Collation
- XI, 240
- Series Title
- NATO Science for Peace and Security Series A: Chemistry and Biology
- Call Number
- -
Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics
The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental princ…
- Edition
- 2
- ISBN/ISSN
- 978-3-319-27596-3
- Collation
- XXII, 483
- Series Title
- Interdisciplinary Applied Mathematics
- Call Number
- -
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