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The Initiation of DNA Replication in Eukaryotes
Every time a cell divides, a copy of its genomic DNA has to be faithfully copied to generate new genomic DNA for the daughter cells. The process of DNA replication needs to be precisely regulated to ensure that replication of the genome is complete and accurate, but that re-replication does not occur. Errors in DNA replication can lead to genome instability and cancer. The process of repl…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-24696-3
- Collation
- XII, 563, 3 b/w illustrations, 84 illustrations in colour
- Series Title
- The Initiation of DNA Replication in Eukaryotes
- Call Number
- -
Animal Models of Behavior Genetics
This stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders. Widely-studied and lesser-used species are examined in models that capture features along the continuum of normative and pathological behavior. The mo…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-1-4939-3777-6
- Collation
- XVI, 389
- Series Title
- Advances in Behavior Genetics
- Call Number
- 616.80076 ANI a
Angiogenesis in Health, Disease and Malignancy
This book is about “Angiogenesis”. A process in which new vasculature is formed from pre-existing capillaries. Angiogenesis process is associated with the proliferation and growth of both physiologically normal and neoplastic tissues, through the formation of vascular supply, essential for delivering growth requirements such as oxygen and nutrients. The book describes more than 100 genes…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-319-28140-7
- Collation
- XVIII, 423
- Series Title
- -
- Call Number
- 574.192 SAL a
The Genetics of Type 2 Diabetes and Related Traits
This book presents the state of the art of type 2 diabetes genetics, from the process of genetic discovery to its interpretation and clinical application, and illustrates a model for other complex human phenotypes. The first section explores genome-wide association studies, the extension of this method to less accessible phenotypes and the arrival of next-generation sequencing. A further secti…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-01574-3
- Collation
- XI, 576, 40 b/w illustrations, 13 illustrations in colour
- Series Title
- The Genetics of Type 2 Diabetes and Related Traits
- Call Number
- -
The Physical Basis of Bacterial Quorum Communication
Quorum sensing (QS) describes a chemical communication behavior that is nearly universal among bacteria. Individual cells release a diffusible small molecule (an autoinducer) into their environment. A high concentration of this autoinducer serves as a signal of high population density, triggering new patterns of gene expression throughout the population. However QS is often much more complex th…
- Edition
- -
- ISBN/ISSN
- 978-1-4939-1402-9
- Collation
- IX, 252
- Series Title
- Biological and Medical Physics, Biomedical Engineering
- Call Number
- -
An Operator Semigroup in Mathematical Genetics
This authored monograph presents a mathematical description of the time evolution of neutral genomic regions in terms of the differential Lyapunov equation. The qualitative behavior of its solutions, with respect to different mutation models and demographic patterns, can be characterized using operator semi group theory. Mutation and drift are two of the main genetic forces, which act on gen…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-642-35958-3
- Collation
- VI, 88
- Series Title
- SpringerBriefs in Applied Sciences and Technology
- Call Number
- 575.1 BOB o
An Introduction to Mathematical Epidemiology
The book is a comprehensive, self-contained introduction to the mathematical modeling and analysis of infectious diseases. It includes model building, fitting to data, local and global analysis techniques. Various types of deterministic dynamical models are considered: ordinary differential equation models, delay-differential equation models, difference equation models, age-structured PDE model…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-1-4899-7612-3
- Collation
- XIV, 453
- Series Title
- Texts in Applied Mathematics
- Call Number
- 576 MAR i
Non-coding RNAs in Colorectal Cancer
This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer.This work further provides the…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-42057-8
- Collation
- VIII, 252
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- -
Non-coding RNA and the Reproductive System
This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts …
- Edition
- 1
- ISBN/ISSN
- 978-94-017-7415-4
- Collation
- VII, 198
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- -
Next Generation Sequencing in Cancer Research, Volume 2
Latest generation sequencing revolutionizes the fields of cancer research and oncology. This follow-up volume focuses more extensively on single cell sequencing of cancer and trials in drug resistance. Another exciting feature is the bioinformatics tools given, that can be used on cancer genome studies. Scientists around the world are attempting to find the root cause of cancer. A reasonable ca…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-15810-5
- Collation
- XVIII, 493
- Series Title
- -
- Call Number
- -
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