This comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines. Twenty-one chapters are divided into four main parts: (I) Background; (2) Delivery Systems for Subunit Vaccines; (3) Delivery Routes, Devices and Dosage Forms; and (4) Pharmaceutical Analysis and Quality Control of Vaccine…
This comprehensive volume presents data describing the role of oxidative stress in anterior eye disease. The content is divided into three logical parts: basic science of the cornea, basic science of the lens, and clinical practices. The first two parts include eighteen chapters that discuss topics ranging from oxidative stress and dry eye disease, endogenous protection of corneal cells against…
This authoritative volume reviews clinical, pathophysiological and therapeutic aspects of oxidative and nitrosative stress in different psychiatric disorders such as schizophrenia, bipolar disorder, autism, and attention deficit hyperactivity disorder (ADHD). Twenty-nine comprehensive chapters are divided into three distinct sections: clinical aspects, pathophysiological aspects, and therapeuti…
This volume examines the current state of free radical biology as it impacts on hepatic disorders. It takes a thorough look at the relationship of oxidative stress in acute and chronic disease and takes into account factors like: redox biomarkers; antioxidant defense and protection; cell signaling, mutations; oxidative damage involving lipids, proteins and nucleic acids; membrane trafficking, i…
This book focuses on data describing the roles of free radicals and related reactive species, and antioxidants, in the causes and treatments of diseases, examining both clinical and pre-clinical trials, as well as basic research. The book is divided into sub-sections with chapters on toxicological mechanisms, agents that produce toxicity, and special topics including areas such as antioxidant s…
This book portrays the commonality of tissue micro-structure that dictates physiological function in various organs (microstructure-function relation). Tissue and organ models are used to illustrate physiological functions based on microstructure. Fiber scale properties such as orientation and crimp are described in detail. Structurally-based constitutive models are given throughout the book, n…
The purpose of this book is to summarize new insights on the structure and function of mountain ecosystems and to present evidence and perspectives on the impact of climate change on biodiversity. This volume describes overall features of high-mountain ecosystems in Japan, which are characterized by clear seasonality and snow-thawing dynamics. Individual chapters cover a variety of unique topic…
The book describes the individual steps necessary for biomacromolecular fragments analysis, as well as a list of essential software tools. For each step, it also shows corresponding web-based tools in detail and provides practical examples of their use.
Christian Pauly demonstrates the strong topological properties of the technologically relevant phase change materials Sb2Te3 and Ge2Sb2Te5 by using two powerful techniques for mapping the surface electronic structure: scanning tunneling spectroscopy (STS) and angle-resolved photoemission spectroscopy (ARPES). In the case of a phase change material, this opens up the possibility of switching bet…
This book shows how tablets (and smartphones) using a variety of selected ‘apps’, can enhance fieldwork and other out-of-classroom activities. The authors review imaginative uses of tablets from their own project and as well as examples from other colleagues. To help readers keep abreast of new technology and innovative ways to use it, the book is supported by a web site and a social media …