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Molecular Pathology in Cancer Research
The aim of the book is to discuss the application of molecular pathology in cancer research, and its contribution in the classification of different tumors and identification of potential molecular targets, as well as how this knowledge may be translated into clinical practice, and the huge impact this field is likely to have in the next 5 to 10 years.
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-6641-7
- Collation
- VIII, 369
- Series Title
- -
- Call Number
- -
Kinesins and Cancer
This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting the importance of kinesins, summarising current knowledge and how they are shown to be crucial for mitosis. Chapters go on to explore how this family of protei…
- Edition
- -
- ISBN/ISSN
- 978-94-017-9732-0
- Collation
- -
- Series Title
- -
- Call Number
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Membrane Protein – Lipid Interactions: Physics and Chemistry in the Bilayer
This book has been conceives as a brief introduction to biomembranes physical chemistry for undergraduate students of sciences, and it is particularly dedicated to the lipid-protein membrane interactions. A general introduction is presented in Chapters 1 and 2. The following Chapters, 3 and 4, describe the most accepted theories on lipid-membrane protein interactions as well as the new experime…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-30275-1
- Collation
- XIV, 116
- Series Title
- Membrane Protein – Lipid Interactions: Physics and Chemistry in the Bilayer
- Call Number
- -
Ion Channels and Transporters of Epithelia in Health and Disease
This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and tran…
- Edition
- -
- ISBN/ISSN
- 978-1-4939-3366-2
- Collation
- -
- Series Title
- -
- Call Number
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ADAMTS13: Biology and Disease
This comprehensive volume discusses the protease ADAMTS13, summarizing the current status of basic and clinical research. The nine authoritative chapters begin with a historical perspective followed by exploration of the biochemistry and structure-function relationships of ADAMTS13 as well as its normal function in hemostasis (cleavage of von Willebrand factor). Emerging research themes for ADA…
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-319-08717-7
- Collation
- X, 186
- Series Title
- -
- Call Number
- 574.192 ADA a
Intrinsically Disordered Proteins Studied by NMR Spectroscopy
This book discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). The properties of IDPs and IDPRs are highly complementary to those deriving from the presence of a unique and well-defined three-dimensional fold. Ignored for a long time in high-resolution studies of proteins, intrin…
- Edition
- -
- ISBN/ISSN
- 978-3-319-20164-1
- Collation
- -
- Series Title
- -
- Call Number
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Multifaceted Roles of Crystallography in Modern Drug Discovery
The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug d…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-9718-4
- Collation
- XI, 240
- Series Title
- NATO Science for Peace and Security Series A: Chemistry and Biology
- Call Number
- -
Multiheme Cytochromes
This brief introduces the structural and functional characterization of this important group of proteins. The content of each chapter is aimed at the non-specialist so that key concepts, methodologies and applications can be presented in a "snapshot" style volume. Multiheme cytochromes are ever more important now that it is possible to obtain genome sequences of microorganisms which have major …
- Edition
- 1
- ISBN/ISSN
- 978-3-642-44960-4
- Collation
- XVI, 39
- Series Title
- SpringerBriefs in Molecular Science
- Call Number
- -
Molecular and Cellular Mechanobiology
This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological reg…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-5615-9
- Collation
- XIII, 302
- Series Title
- Physiology in Health and Disease
- Call Number
- -
Molecular Structures and Structural Dynamics of Prion Proteins and Prions
This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased infectious prions (PrPSc), using MD and MM techniques. As we all know, prion diseases, caused by…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-7317-1
- Collation
- XIX, 355
- Series Title
- Focus on Structural Biology
- Call Number
- -
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