This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker t…
This volume details the essential role of the spiral ganglion neurons. The volume elucidates and characterizes their development, their environment, their electrophysiological characteristics, their connectivity to their targets in the inner ear and the brain, and discusses the potential for their regeneration. A comprehensive review about the spiral ganglion neurons is important for researcher…
This stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders. Widely-studied and lesser-used species are examined in models that capture features along the continuum of normative and pathological behavior. The mo…
This book is a comprehensive illustrated surgical guide to operative exposures of the spinal nerves, also known as peripheral nerves. Each chapter is devoted to a particular nerve and describes the origin, anatomic relations, branches, surgical approaches, and clinical significance. The text is concise and easy to read and is complemented by informative color photos from cadaveric dissections a…
The aim of this book is to present a range of analytical methods that can be used in formulation design and development and focus on how these systems can be applied to understand formulation components and the dosage form these build. To effectively design and exploit drug delivery systems, the underlying characteristic of a dosage form must be understood--from the characteristics of the indiv…
Since information in the brain is processed by the exchange of spikes among neurons, a study of such group dynamics is extremely important in understanding hippocampus dependent memory. These spike patterns and local field potentials (LFPs) have been analyzed by various statistical methods. These studies have led to important findings of memory information processing. For example, memory-trace …
This book presents an analysis of the role of UK building societies, their strengths and weaknesses, and their contribution to the industry, at a time where public confidence in banking is low. Chapters present the results of an empirical analysis of the comparative performance of UK building societies, since the large-scale demutualisation process ended in the year 2000. The authors highlight …
Reviews the most intriguing applications of fractal analysis in neuroscience with a focus on current and future potential, limits, advantages, and disadvantages. Will bring an understanding of fractals to clinicians and researchers also if they do not have a mathematical background, and will serve as a good tool for teaching the translational applications of computational models to students and…
Pendekatan strategis menggunakan peritonektomi dan operasi sitoreduktif untuk mengobati kanker peritoneum telah berkembang secara bertahap selama 30 tahun terakhir yang telah dipancarkan oleh pemimpin kami yang mengesankan, Paul H. Sugarbaker. Dia telah mengumpulkan banyak ahli bedah dari seluruh dunia untuk prosedur ini. Keahliannya membuat banyak dari kita tertarik dengan prosedur peritonekto…
This book provides an overview of neural information processing research, which is one of the most important branches of neuroscience today. Neural information processing is an interdisciplinary subject, and the merging interaction between neuroscience and mathematics, physics, as well as information science plays a key role in the development of this field. This book begins with the anatomy of…