Composed of two extensive sections, this book surveys important work in climate change science, mainly in the United States, and introduces contributions to the body of science that have arrived on the scene between January 2013 and February 2014. The opening section offers a broad examination of contemporary climate change science, with subsections on the Intergovernmental Panel on Climate …
The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug d…
The chapters in this volume stress the need for advances in theoretical understanding to go hand-in-hand with the widespread practical application of forecasting in industry. Forecasting and time series prediction have enjoyed considerable attention over the last few decades, fostered by impressive advances in observational capabilities and measurement procedures. On June 5-7, 2013, an internat…
This monograph opens up new horizons for engineers and researchers in academia and in industry dealing with or interested in new developments in the field of system identification and control. It emphasizes guidelines for working solutions and practical advice for their implementation rather than the theoretical background of Gaussian process (GP) models. The book demonstrates the potential of …
The series Advances in Polymer Science presents critical reviews of the present and future trends in polymer and biopolymer science. It covers all areas of research in polymer and biopolymer science including chemistry, physical chemistry, physics, material science. The thematic volumes are addressed to scientists, whether at universities or in industry, who wish to keep abreast of the importan…
This comprehensive presentation of the integral equation method as applied to electro-analytical experiments is suitable for electrochemists, mathematicians and industrial chemists. The discussion focuses on how integral equations can be derived for various kinds of electroanalytical models. The book begins with models independent of spatial coordinates, goes on to address models in one dimensi…
The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental princ…
These notes describe how to average and fit numerical data that have been obtained either by simulation or measurement. Following an introduction on how to estimate various average values, they discuss how to determine error bars on those estimates, and how to proceed for combinations of measured values. Techniques for fitting data to a given set of models will be described in the second part o…
This book provides a modern introductory tutorial on specialized methodological and applied aspects of spatial and temporal modeling. The areas covered involve a range of topics which reflect the diversity of this domain of research across a number of quantitative disciplines. For instance, the first chapter deals with non-parametric Bayesian inference via a recently developed framework known a…
This brief presents a valuable and concise overview of organocatalytic methodologies in carbohydrate chemistry. It includes glycosylation processes with de novo syntheses of carbohydrates and chain elongation of carbohydrates. The author, an academic of international distinction, goes on to make comparisons between traditional organic and metalorganic transformations.