This book develops and analyses computational wear simulations of the total ankle replacement for the stance phase of gait cycle. The emphasis is put on the relevant design parameters. The book presents a model consisting of three components; tibial, bearing and talar representing their physiological functions.
An argument that the development of scientific practice and growth of scientific knowledge are governed by Darwin's evolutionary model of descent with modification. Although scientific investigation is influenced by our cognitive and moral failings as well as all of the factors impinging on human life, the historical development of scientific knowledge has trended toward an increasingly accu…
How epidemic photography during a global pandemic of bubonic plague contributed to the development of modern epidemiology and our concept of the “pandemic.” In Visual Plague, Christos Lynteris examines the emergence of epidemic photography during the third plague pandemic (1894–1959), a global pandemic of bubonic plague that led to over twelve million deaths. Unlike medical photography…
In praise of imperfection: how life on our planet is a catalog of imperfections, errors, alternatives, and anomalies. In the beginning, there was imperfection, which became the source of all things. Anomalies and asymmetries caused planets to take shape from the bubbling void and sent light into darkness. Life on earth is a catalog of accidents, alternatives, and errors that turned out to wo…
The biological power of the placebo effect. The power of placebos to ameliorate symptoms has been with us for centuries. Western medicine today is finding it increasingly difficult to ignore the efficacy of placebos. In some clinical trials with placebos as controls, inert or sham replicas of active pharmaceutical drugs and even sham surgeries have been found to be as beneficial as the inter…
How the FDA was shaped by public health crises and patient advocacy, told against a background of the contentious hearings on the breast cancer drug Avastin. Food and Drug Administration approval for COVID-19 vaccines and the controversial Alzheimer's drug Aduhelm made headlines, but few of us know much about how the agency does its work. Why is the FDA the ultimate US authority on a drug's …
A lavishly illustrated guide to the magnum opus of the great seventeenth-century anatomist, master embalmer, artist, and collector of specimens. Frederik Ruysch (1638–1731) was a celebrated Dutch anatomist, master embalmer, and museologist. He is best remembered today for strange tableaux, crafted from fetal skeletons and other human remains, that flicker provocatively at the edges of scie…
This SpringerBrief explores the motor performance and biomechanics of golf putting, providing methodologies, studies and approaches to this concept. Presenting outcomes of research published over the past six years, it offers guidelines from a scientifically oriented perspective, and employs new technologies and mathematical methods to assess golf putting. The chapters cover aspects such as pen…
How science is opening up the mysteries of the heart, revealing the poetry in motion within the machine. Your heart is a miracle in motion, a marvel of construction unsurpassed by any human-made creation. It beats 100,000 times every day—if you were to live to 100, that would be more than 3 billion beats across your lifespan. Despite decades of effort in labs all over the world, we have no…
A leading developmental psychologist proposes an evolutionary pathway to human psychological agency. Nature cannot build organisms biologically prepared for every contingency they might possibly encounter. Instead, Nature builds some organisms to function as feedback control systems that pursue goals, make informed behavioral decisions about how best to pursue those goals in the current situ…