Filter by
Multifaceted Roles of Crystallography in Modern Drug Discovery
The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug d…
- Edition
- 1
- ISBN/ISSN
- 978-94-017-9718-4
- Collation
- XI, 240
- Series Title
- NATO Science for Peace and Security Series A: Chemistry and Biology
- Call Number
- -
Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics
The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental princ…
- Edition
- 2
- ISBN/ISSN
- 978-3-319-27596-3
- Collation
- XXII, 483
- Series Title
- Interdisciplinary Applied Mathematics
- Call Number
- -
Modern Proteomics – Sample Preparation, Analysis and Practical Applications
This volume serves as a proteomics reference manual, describing experimental design and execution. The book also shows a large number of examples as to what can be achieved using proteomics techniques. As a relatively young area of scientific research, the breadth and depth of the current state of the art in proteomics might not be obvious to all potential users. There are various books and rev…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-41446-1
- Collation
- IX
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- -
Mitochondrial Function In Vivo Evaluated by NADH Fluorescence
This book covers both the technological development and biomedical applications of NADH fluorescence. Topics covered include perspectives on the history of monitoring NADH fluorescence, the relationship between mitochondrial function and other functions at the tissue level, responses of NADH to physiological and pathophysiological conditions, monitoring of NADH in the human brain and other orga…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-16681-0
- Collation
- XIV
- Series Title
- -
- Call Number
- -
Molecular Pathology in Cancer Research
The aim of the book is to discuss the application of molecular pathology in cancer research, and its contribution in the classification of different tumors and identification of potential molecular targets, as well as how this knowledge may be translated into clinical practice, and the huge impact this field is likely to have in the next 5 to 10 years.
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-6641-7
- Collation
- VIII, 369
- Series Title
- -
- Call Number
- -
Systems Pharmacology and Pharmacodynamics
While systems biology and pharmacodynamics have evolved in parallel, there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline that is the interface between these two methods. This book is the first to cover the expertise from systems biology and pharmacodynamics researchers, desc…
- Edition
- -
- ISBN/ISSN
- 978-3-319-44534-2
- Collation
- XIII, 511
- Series Title
- AAPS Advances in the Pharmaceutical Sciences Series
- Call Number
- -
Modern Optical Spectroscopy
This textbook offers clear explanations of optical spectroscopic phenomena and shows how spectroscopic techniques are used in modern molecular and cellular biophysics and biochemistry. The topics covered include electronic and vibrational absorption, fluorescence, resonance energy transfer, exciton interactions, circular dichroism, coherence and dephasing, ultrafast pump-probe and photon-echo s…
- Edition
- 2
- ISBN/ISSN
- 978-3-662-46776-3
- Collation
- xvi, 572
- Series Title
- -
- Call Number
- -
Bacteria-Metal Interactions
In this book Simona Roccioletti reviews several valuable studies about risk measures and their properties; in particular she studies the new (and heavily discussed) property of "Elicitability" of a risk measure. More important, she investigates the issue related to the backtesting of Expected Shortfall. The main contribution of the work is the application of "Test 1" and "Test 2" developed by A…
- Edition
- -
- ISBN/ISSN
- 978-3-319-18570-5
- Collation
- X, 87
- Series Title
- -
- Call Number
- 574.192
Kinesins and Cancer
This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting the importance of kinesins, summarising current knowledge and how they are shown to be crucial for mitosis. Chapters go on to explore how this family of protei…
- Edition
- -
- ISBN/ISSN
- 978-94-017-9732-0
- Collation
- -
- Series Title
- -
- Call Number
- -
Membrane Protein – Lipid Interactions: Physics and Chemistry in the Bilayer
This book has been conceives as a brief introduction to biomembranes physical chemistry for undergraduate students of sciences, and it is particularly dedicated to the lipid-protein membrane interactions. A general introduction is presented in Chapters 1 and 2. The following Chapters, 3 and 4, describe the most accepted theories on lipid-membrane protein interactions as well as the new experime…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-30275-1
- Collation
- XIV, 116
- Series Title
- Membrane Protein – Lipid Interactions: Physics and Chemistry in the Bilayer
- Call Number
- -
Computer Science, Information & General Works 
Philosophy & Psychology 
Religion 
Social Sciences 
Language 
Pure Science 
Applied Sciences 
Art & Recreation 
Literature 
History & Geography