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Epigenetics - A Different Way of Looking at Genetics
This book presents epigenetics research as a new way of looking at genetics. Topics range from basic epigenetics mechanisms to development of cells and organisms and the biological basis of diseases. In addition the book focuses on immunology and the role of viruses in epigenetics. The last part of the book highlights proteins and peptides as epigenetic modulators.
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- 978-3-319-27186-6
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- 32 b/w illustrations, 9 illustrations in colour
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Intrinsically Disordered Proteins Studied by NMR Spectroscopy
This book discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). The properties of IDPs and IDPRs are highly complementary to those deriving from the presence of a unique and well-defined three-dimensional fold. Ignored for a long time in high-resolution studies of proteins, intrin…
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- 978-3-319-20164-1
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Intestinal Tumorigenesis: Mechanisms of Development & Progression
This volume includes the information necessary to understand recent critical advances in the mechanisms of intestinal tumorigenesis and to comprehend the complexity of the process. The volume aims to entice new researchers to participate in relevant studies, and to provide a forum for discussion within the scientific community to shape future research in this field. Discoveries in intestinal tu…
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- 978-3-319-19986-3
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Stress Response Pathways in Cancer
It is now established that dysregulated cell stress response pathways play a critical role in tumorigenesis, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit cancer patients in the near future. Coauthored by recognized leaders in cancer research from five continents, this novel boo…
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- 978-94-017-9421-3
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Tissue-Specific Stem Cell Niche
This timely volume explores tissue-derived stem cells, summarizing and evaluating the current body of knowledge. Sixteen chapters cover hematopoietic, osteoblast, skeletal, cardiac, pancreatic, epithelial, corneal, hepatic, renal, testicular, ovarian, fingernail, hair follicle and other stem cells- discussing their individual development, functions and pathologies, as well as the commonalities …
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- 978-3-319-21705-5
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- 4 b/w illustrations, 44 illustrations in colour
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Endothelial Signaling in Development and Disease
This book surveys healthy and diseased vascular systems in a multitude of model organisms and systems. It explores a plethora of functions, characteristics, and pathologies of the vascular system such as angiogenesis, fibroblast growth factor signaling, lymphangiogenesis, junctional signaling, the extracellular matrix, vascular permeability, leukocyte extravasation, axon guidance factors, the a…
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- 978-1-4939-2907-8
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- 1 b/w illustrations, 48 illustrations in colour
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Endometrial Stem Cells and Its Potential Applications
Stem cells have ushered in widespread interest and exciting possibilities for cell based therapies. Despite multiple initiatives and meticulous untiring efforts, translating this bench side research into bedside practice and therapies remains a challenge. A better understanding of expanding research in specific areas of stem cells is crucial in developing regenerative medical therapeutics. With…
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- 978-81-322-2746-5
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- 18 b/w illustrations, 2 illustrations in colour
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Endocannabinoids
There is currently considerable interest in the development of medicines that would enhance endocannabinoid-induced “autoprotection”, for example through inhibition of endocannabinoid metabolizing enzymes or cellular uptake processes or that would oppose endocannabinoid-induced “autoimpairment”. This volume describes the physiology, pathophysiology and pharmacology of the endocannabinoi…
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- 978-3-319-20825-1
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- XII, 475
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Stem Cells and Cardiac Regeneration
Ischemic heart disease (IHD) and heart failure (HF) are the major causes of morbidity and mortality in Europe and worldwide. IHD and HF patients could benefi t from therapies that would accelerate natural processes of postnatal collateral vessel formation and/or muscle regeneration. Although treatment for acute myocardial infarction has improved over the past decades, there are currently no …
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- 978-3-319-25427-2
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Neurocytology:Fine Structure of Neurons, Nerve Processes, and Neuroglial Cells
During the second half of the 20th century, the introduction of a variety of new techniques greatly expanded our knowledge of the structure of nerve and neuroglial cells and of the organization of the nervous system at the cellular level. This new information has, however, generally been scattered throughout the literature, making it difficult for investigators to gain an overall vision of the …
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- 1
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- 978-3-319-06855-8
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- XV, 319
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