Mitochondrial disease constitutes a complex and heterogeneous group of disorders resulting from a defect in mitochondrial respiratory chain (MRC) enzyme activity. In view of the dual regulation of the MRC, exercised by both the mitochondrial and nuclear genome, mutations in either mitochondrial or nuclear DNA can result in a MRC deficiency. Whilst a single organ can be affected, MRC disorders o…
This book compiles and presents new developments in statistical causal inference. The accompanying data and computer programs are publicly available so readers may replicate the model development and data analysis presented in each chapter. In this way, methodology is taught so that readers may implement it directly. The book brings together experts engaged in causal inference research to prese…
This volume of the Series SpringerBriefs in Space Life Sciences summarizes the newest finding in the field of mental health and physiological exercise in Space. Currently two major challenges are impacting human health in the western societies, one being a move towards a sedentary society, the second one being longevity. Both have a considerable impact on physical as well as mental health. Spac…
Describes innovative approaches for achieving mixed-reality environments, combining augmented and virtual environments with full-body immersive user interfaces; Offers cost-effective means of body motion capture by hybridizing wearable sensor data; Utilizes energy-efficient micro-embedded sensors for wearable sensing applications; Includes innovative, power autonomous sensing using Bod…
Transnational, interdisciplinary comparison of drug laws and treatment for drug-addicted offenders Explores decisive factors for judges and prosecutors to select treatment instead of punishment options Examines challenges of cooperation between law enforcement and public health for drug treatment, and presents possible solutions
This evidence-rich collection takes on the broad diversity of traumatic stress, in both its causes and outcomes, as well as the wide variety of resources available for recovery. Its accessible coverage shows varied presentations of post-traumatic stress affected by individual, family, and group contexts, including age, previous trauma exposure, and presence or lack of social resources, as well …
This wide-ranging study reviews the state of public health worldwide and presents informed recommendations for real-world solutions. Identifying the most urgent challenges in the field, from better understanding the causes of acute diseases and chronic conditions to reducing health inequities, it reports on cost-effective, science-based, ethically sound interventions. Chapters demonstrate bedro…
This book offers a step-by-step guide to intervention research, including the methods and techniques that researchers, higher degree research students and others can use when pursuing intervention research in schools and other settings. Guided by the Intervention Research Framework, it also provides practical information on linking a program developed using a comprehensive, evidence-based appro…
This book discusses the application of complex adaptive systems theory to the design and evaluation of patient-centered medical homes (PCMHs). The three defining goals of PCMHs are to spread patient-care roles among healthcare team members, focus on disease prevention and include the patient in the healthcare team. It explains why some PCMH pilots are highly successful while others do not show …
Polluted air and contaminated food and water are major causes of human health deterioration, but public health policy has long struggled to effectively address these concerns. This timely book--written for a wide audience of policy makers, researchers, and general readers--synthesizes what we already know about environmental hazards, identifies the gaps in our knowledge, and provides a roadmap …