Formulating Poorly Water Soluble Drugs

The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physio…

Dan Shen (Salvia miltiorrhiza) in medicine.

This book reviews research on Dan Shen, compiles data from clinical trials and biological experiments, and summarizes the latest research advances. It covers the medicinal herb, herbal pieces, and new proprietary drugs that contain it; it also covers simple and compound, traditional and contemporary formulas, and addresses a broad range of subjects, including: standardized cultivation; biodiver…

The Spectrum of Hyperbolic Surfaces

This text is an introduction to the spectral theory of the Laplacian on compact or finite area hyperbolic surfaces. For some of these surfaces, called “arithmetic hyperbolic surfaces”, the eigenfunctions are of arithmetic nature, and one may use analytic tools as well as powerful methods in number theory to study them. After an introduction to the hyperbolic geometry of surfaces, with a …

The Role of Microenvironment in the Control of Tumor Angiogenesis

This work describes the importance of tumor microenvironment in favouring tumor progression and angiogenesis. Under physiological conditions, angiogenesis is dependent on the balance of positive and negative angiogenic modulators within the vascular microenvironment and requires the functional activities of a number of molecules, including angiogenic factors, extracellular matrix proteins, a…

Immunopharmacology

The concept of immunotherapy was in infancy when the first edition was written; since then, major advances have been made, not only with several prominent clinical trials, but also with the approval of cell-based therapy by the FDA for the treatment of cancer in 2010. These events resulted in a gradually narrowing gap between early scientific knowledge and the late development of immune-based …

Ocular Drug Delivery: Advances, Challenges and Applications

The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major challenge to drug delivery researchers. There are on-going studies, in search of treatment especially for the diseases affecting the posterior segment of the eye. This book gives an…

Novel Natural Products: Therapeutic Effects in Pain, Arthritis and Gastro-int…

Edition

1

ISBN/ISSN

978-3-0348-0927-6

Collation

VII, 286

Series Title

Progress in Drug Research

Call Number

-

Novel Immunotherapeutic Approaches to the Treatment of Cancer:Drug Developmen…

Cancer care is undergoing a radical transformation as novel technologies are directed toward new treatments and personalized medicine. The most dramatic advances in the treatment of cancer have come from therapeutics that augment the immune response to tumors. The immune checkpoint inhibitors are the best-known and most highly advanced examples of Immune Therapeutics targeting tumor cells and i…

Noncovalent Forces

Computational methods, and in particular quantum chemistry, have taken the lead in our growing understanding of noncovalent forces, as well as in their categorization. This volume describes the current state of the art in terms of what we now know, and the current questions requiring answers in the future. Topics range from very strong (ionic) to very weak (CH--π) interactions. In the intermed…

Antibody-Drug Conjugates: The 21st Century Magic Bullets for Cancer

This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker t…