Development of strategies to assist the movement of poorly permeable molecules across biological barriers has long been the goal of drug delivery science. In the last three decades, there has been an exponential increase in advanced drug delivery systems that aim to address this issue. However, most proprietary delivery technologies that have progressed to clinical development are based on perm…
Plants have served mankind as an important source of foods and medicines. While we all consume plants and their products for nutritional support, a majority of the world population also rely on botanical remedies to meet their health needs, either as their own “traditional medicine” or as “complementary and alternative medicine”. From a pharmaceutical point of view, many compounds obtai…
This Special Issue book, “Natural Products for Cancer Prevention and Therapy”, is based on recent advances in natural products for cancer prevention and therapy. For this purpose, the authors of this book have been organizing a biennial international conference series. The first meeting (First International Conference on Natural Products for Cancer Prevention and Therapy) was held in Istanb…
This book constitutes a key reference on the use of algae in the biopharmaceuticals production field; providing an updated outlook on the achievements accomplished thus far and transmitting a prospective view for this biotechnological application. This book provides a detailed description of the technology as well as an updated outlook of the strides achieved thus far in the field of algae-b…
This book provides a detailed account of the most recent developments, challenges and solutions to seamlessly advance and launch a lyophilized biologics or vaccine product, based on diverse modalities, ranging from antibodies (e.g., monoclonal, fused), complex biologics (e.g., antibody drug conjugate, PEGylated proteins), and vaccines (e.g., recombinant-protein based). The authors adeptly guide…
Beragam objek koleksi Whipple Museum of the History of Science yang terkenal secara internasional dibuat lega oleh sejumlah sejarawan sains yang sangat dihormati dalam empat belas esai. Setiap bab berfokus pada instrumen atau kelompok objek tertentu, mulai dari astrolabe abad pertengahan Inggris hingga 'indikator sumber benih' pertanian modern hingga koleksi kepala ayam plester yang aneh. Para …
Once feared and misunderstood even among the medical community, epilepsy has since largely been demystified. Besides the characteristic seizures, various cognitive, behavioral, and emotional difficulties are recognized as associated with the condition, and patients are finding relief in medical management and/or surgical intervention. Not surprisingly, neuropsychology has emerged as a major com…
A number of leading experts in neuroscience including intermediary metabolism, enzymology and transporter physiology have contributed to this book which provides comprehensive discussions of these different aspects of the functional importance of the glutamate-glutamine cycle coupling homeostasis of glutamatergic, excitatory neurotransmission to basic aspects of brain energy metabolism. This bo…
This open access book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related func…
This new edition highlights the numerous advances made in the field of microbial endocrinology over the last five years. Prominent among these new topics featured is the emergence of the microbiota-gut-brain axis and the role it plays in brain function. Specific focus is given to the role of microbial endocrinology in the evolutionary symbiosis between man and microbe as it relates to both heal…