This book, the second of two volumes on the Gentianaceae, is devoted to aspects of biotechnology and their applications. It consists of 18 chapters and covers micropropagation by means of organogenesis or somatic embryogenesis, and single cell manipulation of various species belonging to the horticultural genera Blakstonia, Centaurium, Gentiana, Gentianalla and Swertia. Furthermore, the applica…
This book explores emerging pedagogical perspectives based on the design of new learning spaces supported by digital technologies and brings together some of the best research in this field. The book is divided into three themes: foundations of emerging pedagogies, learning designs for emerging pedagogies and, adaptive and personalized learning. The chapters provide up-to-date information about…
Twenty-five years ago there was increasing optimism in policy, curriculum and research about the contribution that technology education might make to increased technological literacy in schools and the wider population. That optimism continues, although the status of technology as a learning area remains fragile in many places. This edited book is offered as a platform from which to continue…
The Magnitude 9 Great East Japan Earthquake on March 11, 2011, followed by a massive tsunami struck TEPCO’s Fukushima Daiichi Nuclear Power Station and triggered an unprecedented core melt/severe accident in Units 1 – 3. The radioactivity release led to the evacuation of local residents, many of whom still have not been able to return to their homes. As a group of nuclear experts, the A…
These lecture notes present a concise and introductory, yet as far as possible coherent, view of the main formalizations of quantum mechanics and of quantum field theories, their interrelations and their theoretical foundations. The “standard” formulation of quantum mechanics (involving the Hilbert space of pure states, self-adjoint operators as physical observables, and the probabilisti…
The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin …
Tobias Buchmann analyzes innovation network dynamics in the German automotive industry. The study is based on a model for analyzing the complex evolution of innovation networks and the driving mechanisms underlying network evolution derived from theoretical and empirical findings in innovation economics, economic geography and management science. The author uses established social network analy…
For more than 30 years, certain governments, individuals and organisations have actively promoted computers as learning technologies. Enormous amounts of money and time have been spent promoting specific kinds of educational computing, and policies by which these might be implemented. The view that computers can enhance student learning has gained broad acceptance. The computers should not auto…
This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are …
This book presents basic and extensive information on the physiological and pathological significance of the protein-modifying enzymes, transglutaminases, which are involved in multiple biological events by catalyzing a unique and important posttranslational modification reaction, cross-linking of proteins, and interacting with a large number of proteins inside and outside of cells. Although se…