Semantic change — how the meanings of words change over time — has preoccupied scholars since well before modern linguistics emerged in the late 19th and early 20th century, ushering in a new methodological turn in the study of language change. Compared to changes in sound and grammar, semantic change is the least understood. Ever since, the study of semantic change has progressed steadily,…
Antimicrobial resistance remains a major concern in medicine, especially during the COVID-19 pandemic, where microbial infections were frequent complications. To combat drug-resistant pathogens, there has been a renewed interest in the use of antimicrobial peptides (AMPs). This reprint focuses on the in-silico approaches used for the rational discovery and design of AMPs. Such computational met…
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researcher…
Computational and Numerical Simulations is an edited book including 20 chapters. Book handles the recent research devoted to numerical simulations of physical and engineering systems. It presents both new theories and their applications, showing bridge between theoretical investigations and possibility to apply them by engineers of different branches of science. Numerical simulations play a key…
Nowadays, computational and mathematical methods provide effective tools for handling vast quantities of data and information in the fields of big data analytics, knowledge discovery and decision-making for solving complex problems in the world. The present reprint contains all of the articles accepted and published in the first edition of the Special Issue titled “Computational and Mathemati…
This book presents recent studies of acoustic wave propagation through different media including the atmosphere, Earth's subsurface, complex dusty plasmas, porous materials, and flexible structures. Mathematical models of the underlying physical phenomena are introduced and studied in detail. With its seven chapters, the book brings together important contributions from renowned international r…
The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple…
What is online risk? How can we best protect children from it? Who should be responsible for this protection? Is all protection good? Can Internet users trust the industry? These and other fundamental questions are discussed in this book. Beginning with the premise that the political and democratic processes in a society are affected by the way in which that society defines and perceives risks,…
This open access book explores how legal proceedings in and out-of-court can be matched to the complex problems underlying disputes concerning child custody, residence and contact between parents. It focusses in particular on Nordic experiences of in and out-of-court mechanisms as means of resolving custody disputes. The contributors are internationally renowned and experienced researchers f…
This book is available as open access through the Bloomsbury Open Access programme and is available on www.bloomsburycollections.com. Despite their very different histories, societies, political and legal systems, Russia and the UK stand out as favouring a punitive approach to young law breakers, imprisoning many more children than any other European countries. The book is based on the author's…