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Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems
The book presents a new, powerful model of neuronal networks, consisting of a three-dimensional neuronal culture in which 3D neuronal networks are coupled to micro-electrode-arrays (MEAs). It discusses the main advantages of the three-dimensional system compared to its two-dimensional counterpart, and shows that the network dynamics, recorded during both spontaneous and stimulated activity, dif…
- Edition
- 1
- ISBN/ISSN
- 2190-5053
- Collation
- XIII, 148
- Series Title
- Springer Theses
- Call Number
- -
Neural Stem Cells in Development, Adulthood and Disease
This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disea…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-1907-9
- Collation
- XXI, 202
- Series Title
- Stem Cell Biology and Regenerative Medicine
- Call Number
- -
Myeloid-Derived Suppressor Cells and Cancer
The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells,…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-26819-4
- Collation
- IX, 102
- Series Title
- SpringerBriefs in Immunology
- Call Number
- -
Molecular and Cellular Mechanobiology
This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological reg…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-5615-9
- Collation
- XIII, 302
- Series Title
- Physiology in Health and Disease
- Call Number
- -
Molecular and Cellular Biology of Platelet Formation
This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and r…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-39560-9
- Collation
- X, 460
- Series Title
- -
- Call Number
- -
Molecular Pathology in Cancer Research
Cancer Biology, Medical Genetics, Cell Biology, Protein Biochemistry, Molecular Genetics
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-6641-7
- Collation
- VIII, 369
- Series Title
- -
- Call Number
- -
Molecular Mechanisms of Cell Differentiation in Gonad Development
This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of th…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-31971-1
- Collation
- XII, 434
- Series Title
- Results and Problems in Cell Differentiation
- Call Number
- -
The Serpin Family
The book provides an comprehensive overview on biology, genetics and cellular functions of serpins (serine protease inhibitors) in health and disease. With over 1000 members serpins are the most diverse family of protease inhibitors. Latest groundbreaking research findings are presented and broaden the understanding on inhibitory and non-inhibitory serpins, not only in mammalian organisms but a…
- Edition
- -
- ISBN/ISSN
- 978-3-319-22711-5
- Collation
- -
- Series Title
- -
- Call Number
- -
Elucidation of Abiotic Stress Signaling in Plants Functional Genomics Perspe…
Abiotic stresses such as high temperature, low-temperature, drought, and salinity limit crop productivity worldwide. Understanding plant responses to these stresses is essential for rational engineering of crop plants. In Arabidopsis, the signal transduction pathways for abiotic stresses, light, several phytohormones and pathogenesis have been elucidated. A significant portion of plant genomes …
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-2540-7
- Collation
- 1 b/w illustrations, 26 illustrations in colour
- Series Title
- -
- Call Number
- -
Elucidation of Abiotic Stress Signaling in Plants Functional Genomics Perspe…
Abiotic stresses such as high temperature, low-temperature, drought, and salinity limit crop productivity worldwide. Understanding plant responses to these stresses is essential for rational engineering of crop plants. In Arabidopsis, the signal transduction pathways for abiotic stresses, light, several phytohormones and pathogenesis have been elucidated. A significant portion of plant genom…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-2211-6
- Collation
- 6 b/w illustrations, 29 illustrations in colour
- Series Title
- -
- Call Number
- -
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