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Toxicological Risk Assessment for Beginners
This book serves as a comprehensive introductory guide to the practical aspects of risk assessment. Chapters include clearly defined objectives and summaries. The book includes: hazard identification, dose-response, exposure assessment, risk characterization, chemical mixtures, epidemiology, emerging issues and global perspectives with accessible language. The book concludes with a set of hypot…
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- 978-3-319-12751-4
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Toxicity and Autophagy in Neurodegenerative Disorders
Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotecti…
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- 978-3-319-13939-5
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Cyanobacteria for bioremediation of wastewaters
This book reflects the use of cyanobacteria for the bioremediation of wastewater through different mechanisms and pathways of transformation and transfer of hazardous substances from one medium to another. The application of microorganisms for bioremediation is determined by their ubiquity, small size, high rate of reproduction and large surface-to-volume cell ratio. Mechanisms of interaction o…
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- ISBN/ISSN
- 9783319267517
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- ix, 124 pages
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- Call Number
- 572
Inflammation: the Common Link in Brain Pathologies
This unifying theme of this book-with sections on mechanisms of defense and neuropathogenesis, neurological diseases, infections of the nervous system, neuropharmacology, and novel therapies-is interactions of the immune and nervous systems. It also discusses the role of inflammation as a key mediator of different brain disorders. There have been significant scientific advances in the multidisc…
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- 978-981-10-1710-0
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- X, 345
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- 611 INF
Towards Green Lubrication in Machining
The book gives an overview of environmental friendly gaseous and vapour, refrigerated compressed gas, solid lubricant, mist lubrication, minimum quantity lubrication (MQL) and vegetable oils that can be used as lubricants and additives in industrial machining applications. This book introduces vegetable oils as viable and good alternative resources because of their environmental friendly, non-t…
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- 978-981-287-266-1
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Cytochrome P450 Structure, Mechanism, and Biochemistry
This authoritative Fourth Edition summarizes the advances of the past decade concerning the structure, mechanism, and biochemistry of cytochrome P450 enzymes, with sufficient coverage of earlier work to make each chapter a comprehensive review of the field. Thirteen chapters are divided into two detailed volumes, the first covering the fundamentals of cytochrome P450 biochemistry, as well as th…
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- ISBN/ISSN
- 9783319121086
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- x, 912 pages
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- 572
D-amino acids : physiology, metabolism, and application
This book presents a comprehensive overview of the roles of ᴅ-amino acids and latest research findings, to reveal their fascinating aspects and to facilitate better understanding of their important roles in physiology and diseases. It also provides useful hints for the development of drugs and functional foods. ᴅ-Amino acids were once called unnatural amino acids and were considered to be i…
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- 9784431560777
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- ix, 357 pages
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- 572
Total Synthesis of Thielocin B1 as a Protein-Protein Interaction Inhibitor of…
This book focuses on thielocin B1 (TB1), which was found to be an inhibitor of protein–protein interactions (PPIs) of proteasome assembling chaperone (PAC) 3 homodimer, and elucidates the mechanism by nuclear magnetic resonance (NMR) studies. Interfaces of PPIs recently have been expected to be novel therapeutic targets, while it is difficult to apply conventional methodology based on lock an…
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- 978-4-431-55447-9
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Fossil Matter in the Geosphere
The first volume in this new text book series covers comprehensively relevant aspects related to the appearance and characterisation of fossil matter in the geosphere such as kerogen, oil, shales and coals. As organic geochemistry is a modern scientific subject characterized by a high transdisciplinarity and located at the edge of chemistry, environmental sciences, geology and biology, there cl…
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- 978-3-319-11938-0
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- VIII, 158 pages
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- Fundamentals in Organic Geochemistry
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Self-Assembled Molecules – New Kind of Protein Ligands
The standard substrate complexation mechanism engages natural binding sites. In contrast, supramolecular structures may form complexes with proteins by penetrating in regions which are either naturally unstable or become temporarily accessible due to structural rearrangements related to the protein’s function. This may result in enhancement of irreversible processes (e.g. immune complexat…
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- ISBN/ISSN
- 978-3-319-65639-7
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- 540 SEL
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