Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions …
Every time a cell divides, a copy of its genomic DNA has to be faithfully copied to generate new genomic DNA for the daughter cells. The process of DNA replication needs to be precisely regulated to ensure that replication of the genome is complete and accurate, but that re-replication does not occur. Errors in DNA replication can lead to genome instability and cancer. The process of repl…
Initially caught helplessly between well-meaning fellow scientists, the government and more sinister agents, Michelle, with the help of a host of unlikely heroes, eventually takes control and finds the courage to confront the decision of whether to save human lives or humanity.
This monograph presents complex data on Fascioloides magna from all aspects of its research (general information, distribution, spectrum of hosts) and summarizes the latest information on molecular structure of informative genes which were recently applied in resolving taxonomy and biogeography of this veterinary important parasite. The giant liver fluke, Fascioloides magna, is important liver …
This book offers a comprehensive overview of medullary thyroid carcinoma, both in the more common sporadic form and in the familial form, multiple endocrine neoplasia (MEN) types 2A and 2B. The coverage includes, but is not limited to, molecular biology and genetics, pathology, clinical presentation, imaging techniques, surgical treatment, and follow-up. The role of calcitonin as a highly sensi…
In this thesis two variants of the fast variable elimination method are developed. They are intuitive, simple to implement and give results which are in very good agreement with those found from numerical simulations. The relative simplicity of the techniques makes them ideal for applying to problems featuring demographic stochasticity, for experts and non-experts alike. Within the context of …
This book, written by very well known opinion leaders in the field, covers all aspects of familial Mediterranean fever, the most common monogenic autoinflammatory disease. The opening chapters explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies. A large part of the book is then devoted to a detailed description of the typi…
Dr. Vipin Chandra Kalia is presently working as Chief Scientist at Microbial Biotechnology and Genomics, CSIR-Institute of Genomics and Integrative Biology, Delhi. He is a Professor of Academy of Scientific and Innovative Research (AcSIR), Delhi. He obtained his M.Sc. and Ph.D. degrees in Genetics from the Indian Agricultural Research Institute, New Delhi. He has been elected as: (1) Fellow of …
The performance of crops in the soil largely depends on the physico-chemical components of the soil, which regulate the availability of nutrients as well as abiotic and biotic stresses. Microbes are the integral component of any agricultural soil, playing a vital role in regulating the bioavailability of nutrients, the tolerance to abiotic and biotic stresses and management of seed-borneand soi…
The performance of crops in the soil largely depends on the physico-chemical components of the soil, which regulate the availability of nutrients as well as abiotic and biotic stresses. Microbes are the integral component of any agricultural soil, playing a vital role in regulating the bioavailability of nutrients, the tolerance to abiotic and biotic stresses and management of seed-borneand soi…