The Neuropathology of Huntington’s Disease: Classical Findings, Recent Deve…

This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correla…

Field Guidelines for Genetic Experimental Designs in High-Throughput Sequencing

Edition

-

ISBN/ISSN

978-3-319-31350-4

Collation

XI, 399

Series Title

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Call Number

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Fiber Plants Biology, Biotechnology and Applications

This book assesses the potential effects of biotechnological approaches, particularly genetic modification, on the present state of fiber crop cultivation and sustainable production. Leading international researchers discuss and explain how biotechnology can affect and solve problems in connection with fiber crops. The topics covered include biology, biotechnology, genomics and applications of …

Alien Introgression in Wheat: Cytogenetics, Molecular Biology, and Genomics

This book provides an overview of the latest advancements in the field of alien introgression in wheat. The discovery and wide application of molecular genetic techniques including molecular markers, in situ hybridization, and genomics has led to a surge in interspecific and intergeneric hybridization in recent decades. The work begins with the taxonomy of cereals, especially of those species w…

The Male Role in Pregnancy Loss and Embryo Implantation Failure

Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions …

The Initiation of DNA Replication in Eukaryotes

​Every time a cell divides, a copy of its genomic DNA has to be faithfully copied to generate new genomic DNA for the daughter cells. The process of DNA replication needs to be precisely regulated to ensure that replication of the genome is complete and accurate, but that re-replication does not occur. Errors in DNA replication can lead to genome instability and cancer. The process of repl…

The Hunt for FOXP5

Initially caught helplessly between well-meaning fellow scientists, the government and more sinister agents, Michelle, with the help of a host of unlikely heroes, eventually takes control and finds the courage to confront the decision of whether to save human lives or humanity.

The Giant Liver Fluke, Fascioloides magna: Past, Present and Future Research

This monograph presents complex data on Fascioloides magna from all aspects of its research (general information, distribution, spectrum of hosts) and summarizes the latest information on molecular structure of informative genes which were recently applied in resolving taxonomy and biogeography of this veterinary important parasite. The giant liver fluke, Fascioloides magna, is important liver …

Medullary Thyroid Carcinoma

This book offers a comprehensive overview of medullary thyroid carcinoma, both in the more common sporadic form and in the familial form, multiple endocrine neoplasia (MEN) types 2A and 2B. The coverage includes, but is not limited to, molecular biology and genetics, pathology, clinical presentation, imaging techniques, surgical treatment, and follow-up. The role of calcitonin as a highly sensi…

Fast Variables in Stochastic Population Dynamics

In this thesis two variants of the fast variable elimination method are developed. They are intuitive, simple to implement and give results which are in very good agreement with those found from numerical simulations. The relative simplicity of the techniques makes them ideal for applying to problems featuring demographic stochasticity, for experts and non-experts alike. Within the context of …