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Modified Nucleic Acids in Biology and Medicine
This volume is comprised of 18 chapters, covering various aspects of DNA modification and RNA modified bases. It also discusses in detail circular RNA, therapeutic oligonucleotides and their different properties. The chemical nature of DNA, RNA, protein and lipids makes these macromolecules easily modifiable, but they are also susceptible to damage from both endogenous and exogenous agents. …
- Edition
- 1
- ISBN/ISSN
- 2197-9758
- Collation
- XIV, 453
- Series Title
- RNA Technologies
- Call Number
- -
Molecular Mechanisms of Cell Differentiation in Gonad Development
This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of th…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-31971-1
- Collation
- XII, 434
- Series Title
- Results and Problems in Cell Differentiation
- Call Number
- -
Molecular Genetics of Pediatric Orthopaedic Disorders
In the past two decades we have seen a surge forward in understanding the genetics and biochemistry underlying many pediatric orthopaedic disorders. A few projects have even progressed into the realm of clinical trials that are primarily aimed at controlling progressive disease. Meanwhile, genomic technology development has outpaced expectations and is enabling gene discovery for disorders that…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-2168-3
- Collation
- XII, 168
- Series Title
- Springer New York, NY
- Call Number
- -
Monooxygenase, Peroxidase and Peroxygenase Properties and Mechanisms of Cytoc…
This book describes in 13 chapters mechanisms of P450 used to monooxygenate substrates via the NAD(P)H/O2 pathway using its peroxidase and peroxygenase functions. P450 also utilizes peroxides, peracids, periodate and iodosobenzene to oxygenate substrates via the shunt pathway. Also described are mechanisms used in the oxidation of pharmaceuticals by CYP3A4; acyl- carbon cleavage by CYP17A1, CYP…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-16008-5
- Collation
- XV, 368
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- -
The Serpin Family
The book provides an comprehensive overview on biology, genetics and cellular functions of serpins (serine protease inhibitors) in health and disease. With over 1000 members serpins are the most diverse family of protease inhibitors. Latest groundbreaking research findings are presented and broaden the understanding on inhibitory and non-inhibitory serpins, not only in mammalian organisms but a…
- Edition
- -
- ISBN/ISSN
- 978-3-319-22711-5
- Collation
- -
- Series Title
- -
- Call Number
- -
Elispot for Rookies (and Experts Too)
This book provides basic, simple, and logical explanations for choices to be made to run the best Elispot possible. It allows the newcomer to truly understand the best options for specific protocol steps, reagents and materials, and provides even the experienced Elispot user with insight into best practices. The techniques presented here are supported by the author’s twenty-plus years of firs…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-45295-1
- Collation
- 7 b/w illustrations, 32 illustrations in colour
- Series Title
- -
- Call Number
- -
MicroRNAs and Other Non-Coding RNAs in Inflammation
The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e. rheumatoid arthritis, Crohn’s disease, diabetes) and innate immunity. It provides a universal reference work comprising both basic and specialized information. Given that ncRNAs represent new th…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-13688-2
- Collation
- X, 237
- Series Title
- Progress in Inflammation Research
- Call Number
- -
Electron Spin Resonance (ESR) Based Quantum Computing
This book addresses electron spin-qubit based quantum computing and quantum information processing with a strong focus on the background and applications to EPR/ESR technique and spectroscopy. It explores a broad spectrum of topics including quantum computing, information processing, quantum effects in electron-nuclear coupled molecular spin systems, adiabatic quantum computing, heat bath algor…
- Edition
- 1
- ISBN/ISSN
- 978-1-4939-3658-8
- Collation
- 43 b/w illustrations, 62 illustrations in colour
- Series Title
- -
- Call Number
- -
Medicine as a Scholarly Field: An Introduction
To me it is astonishing and to medicine actually shameful that it has taken up to year 2015 before there is a work in which the essence of medicine is described and discussed." -- J. Steurer, University of Zurich "[In this book], Miettinen beautifully elucidates the concepts and principles of knowledge-based diagnosis, and prognosis, within medicine. Now, after six decades of keen ob…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-19011-2
- Collation
- XVI, 136
- Series Title
- Medicine as a Scholarly Field: An Introduction
- Call Number
- -
MicroRNAs and Other Non-Coding RNAs in Inflammation
The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e. rheumatoid arthritis, Crohn’s disease, diabetes) and innate immunity. It provides a universal reference work comprising both basic and specialized information. Given that ncRNAs represent new th…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-13688-2
- Collation
- X, 237
- Series Title
- Progress in Inflammation Research
- Call Number
- -
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