This monograph is the first easy-to-read-and-understand book on prion proteins' molecular dynamics (MD) simulations and on prions' molecular modelling (MM) constructions. It enables researchers to see what is crucial to the conformational change from normal cellular prion protein (PrPC) to diseased infectious prions (PrPSc), using MD and MM techniques. As we all know, prion diseases, caused by…
This book constitutes the proceedings of the 12th European Conference on Multi-Agent Systems, EUMAS 2014, held in Prague, Czech Republic, in December 2014. The 21 full papers and 8 short papers presented in this volume were carefully reviewed and selected from 79 submissions. They are organized in topical sections named: agent-based models, trust and reputation; coordination, coalitions and tea…
This book outlines a unified theory of embryonic development, assuming morphogenesis to be a multi-level process including self-organizing steps while also obeying general laws. It is shown how molecular mechanisms generate mechanical forces, which in the long run lead to morphological changes. Questions such as how stress-mediated feedback acts at the cellular and supra-cellular levels and ho…
This contributed volume aims to reconsider the concept of individuation, clarifying its articulation with respect to contemporary problems in perceptual, neural, developmental, semiotic and social morphogenesis. The authors approach the ontogenetical issue by taking into account the morphogenetic process, involving the concept of individuation proposed by Gilbert Simondon and Gilles Deleuze. Th…
This book provides a comprehensive overview of key technologies being used to address challenges raised by continued device scaling and the extending gap between memory and central processing unit performance. Authors discuss in detail what are known commonly as “More than Moore” (MtM), technologies, which add value to devices by incorporating functionalities that do not necessarily scale a…
This book provides essential background knowledge on the development of model-based real-world solutions in the field of control and decision making for water systems. It presents system engineering methods for modelling surface water and groundwater resources as well as water transportation systems (rivers, channels and pipelines). The models in turn provide information on both the water quant…
Interested in iPhone and iPad apps development? Want to learn more? Whether you are a relative newcomer to iPhone and iPad or iOS development or an old hand looking to expand your horizons, we have the perfect Swift-flavored book for you. The update to the bestselling More iPhone Development by Dave Mark and Jeff LaMarche, More iPhone Development with Swift digs deeper into the new Apple Swift…
If you are looking to extend your iOS programming skills beyond the basics then More iPhone Development with Objective-C is for you. Authors Dave Mark, Jayant Varma, Jeff LaMarche, Alex Horovitz, and Kevin Kim explain concepts as only they can—with code snippets you can customize and use, as you like, in your own apps. More iPhone Development with Objective-C is an independent companion to B…
The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the fl…
This proceedings volume covers the proceedings of ERCICA 2015. ERCICA provides an interdisciplinary forum for researchers, professional engineers and scientists, educators, and technologists to discuss, debate and promote research and technology in the upcoming areas of Computing, Information, Communication and their Applications. The contents of this book cover emerging research areas in field…