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Translational Neuropsychopharmacology
This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importa…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-33911-5
- Collation
- XII, 498
- Series Title
- Current Topics in Behavioral Neurosciences
- Call Number
- -
Translational Approaches to Autism Spectrum Disorder
This book addresses and synthesizes recent basic, translational, and clinical research with the goal of understanding the mechanisms behind autism spectrum disorder (ASD) and how they lead to altered brain function and behavior. Bringing clarity to these mechanisms will lead to more effective therapies for the various heterogeneous pathologies that comprise ASD. Currently there are few, if any,…
- Edition
- 1
- ISBN/ISSN
- 978-3-319-38657-7
- Collation
- XIV, 218
- Series Title
- -
- Call Number
- -
Evacuation Modeling Trends
This book presents an overview of modeling definitions and concepts, theory on human behavior and human performance data, available tools and simulation approaches, model development, and application and validation methods. It considers the data and research efforts needed to develop and incorporate functions for the different parameters into comprehensive escape and evacuation simulations, wit…
- Edition
- -
- ISBN/ISSN
- 978-3-319-20708-7
- Collation
- VII, 133
- Series Title
- -
- Call Number
- -
Translating Molecular Biomarkers into Clinical Assays
This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are …
- Edition
- 1
- ISBN/ISSN
- 978-3-319-40793-7
- Collation
- XIII, 212
- Series Title
- AAPS Advances in the Pharmaceutical Sciences Series
- Call Number
- -
Transglutaminases
This book presents basic and extensive information on the physiological and pathological significance of the protein-modifying enzymes, transglutaminases, which are involved in multiple biological events by catalyzing a unique and important posttranslational modification reaction, cross-linking of proteins, and interacting with a large number of proteins inside and outside of cells. Although se…
- Edition
- 1
- ISBN/ISSN
- 978-4-431-55823-1
- Collation
- VIII, 391
- Series Title
- -
- Call Number
- -
Systemic Corticosteroids for Inflammatory Disorders in Pediatrics
This comprehensive volume provides current state of the art of the use of corticosteroids in the pediatric patient. It consists of 14 chapters written by leading authors from different countries. The first chapters cover historical notes, general concepts on treatment with corticosteroids with regard to indications and side effects, and basic pharmacologic properties of these compounds. The res…
- Edition
- -
- ISBN/ISSN
- 978-3-319-16056-6
- Collation
- VI, 184
- Series Title
- -
- Call Number
- -
Judicial Application of International Law in Southeast Europe
This edited volume presents comparative research on how the courts in Southeast Europe apply international law. After the introductory Part I, Part II discusses specific areas of international law, notably the law of Association Agreements between the EU and third countries, the law of the World Trade Organization, and international environmental law (the Aarhus Convention). Part III consists o…
- Edition
- -
- ISBN/ISSN
- 978-3-662-46384-0
- Collation
- -
- Series Title
- -
- Call Number
- -
Judicial Activism: An Interdisciplinary Approach to the American and European…
This volume offers different perspectives on judicial practice in the European and American contexts, both arguably characterized in the last decades by the emergence of novel normative and even policy arguments by judges. The central question deserving the attention of the contributors concerns the degree in which judicial exercises in practical reasoning may amount to forms of judicial usurpa…
- Edition
- -
- ISBN/ISSN
- 978-3-319-18549-1
- Collation
- -
- Series Title
- -
- Call Number
- -
Systematic Changes in Body Image Following Formation of Phantom Limbs
This book presents new findings on body image and also introduces new neuroscience-based methods for the fields of neurology and neurorehabilitation. Even when the hand is stationary we know its position – information that is needed by the brain to plan movements. If the sensory input from a limb is removed as the result of an accident, or as part of an experiment with local anesthesia, then …
- Edition
- -
- ISBN/ISSN
- 978-981-10-1460-4
- Collation
- VII, 59
- Series Title
- SpringerBriefs in Biology
- Call Number
- -
European Perspectives on the Common European Sales Law
This book presents a complete and coherent view of the subject of Common European Sales Law from a range of European perspectives. The book offers a comparison of the CESL with the CISG, as well as pre-existing instruments, including the Draft Common Frame of Reference (DCFR) and the Principles of European Contract Law (PECL). It analyses the process of enactment of CESL and its scope of applic…
- Edition
- -
- ISBN/ISSN
- 978-3-319-10497-3
- Collation
- 1 b/w illustrations
- Series Title
- -
- Call Number
- -
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