Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. However, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under v…
Thrombolytic therapy is finally starting to reach patients in a variety of settings all over the world. Formerly in the domain of sub-specialists, thrombolytic therapy now rests in the realm of Emergency Medicine, Intensive Care, Vascular, and Neuro hospital Medicine physicians. Increasingly, non-neurologists use thrombolytic therapy. This is a significant advancement since the 2nd edition to T…
This book presents contributions from researchers, practitioners and professional institutions that published papers in the Proceedings of the Educating Enterprising Engineers and Scientists conference, held in London, UK on 17th June 2015. The topics considered range from educating engineers to giving a business edge and embedding entrepreneurship to achieve integrated education and curriculum…
The introduction of techniques that permit visualization of the human nervous system is one of the foremost advances in neuroscience and brain-related research. Among the most recent significant developments in this respect are ultra-high field MRI and the image post-processing technique known as track density imaging (TDI). It is these techniques (including super-resolution TDI) which represen…
The inaugural publication of the 7.0 Tesla MRI Brain Atlas: In Vivo Atlas with Cryomacrotome Correlation in 2010 provided readers with a spectacular source of ultra-high resolution images revealing a wealth of details of the brainstem and midbrain structures. This second edition contributes additional knowledge gained as a result of technologic advances and recent research. To facilitate identi…
Endovascular neurosurgery is a recently introduced but rapidly evolving medical field, which uses minimally invasive interventions to treat major life-threatening vascular lesions of the Central Nervous System. Although its history counts less than 15 years of worldwide acceptance, it has rapidly displaced the traditional open neurosurgical techniques, being nowadays the first treatment choice …
This volume showcases contributions from leading academics, educators and policymakers derived from two workshops hosted by the Interdisciplinary Center for Economic Science (ICES) at George Mason University on internationalization and competitiveness. It aims to present key areas of current research and to identify basic problems within the field to promote further discussion and research. …
This is the first book on the market that explores the importance of curcumin for the treatment of neurological disorders. It has been estimated that 35.6 million people globally had dementia in 2010 and the prevalence of dementia has been predicted to double every 20 years. Thus, 115.4 million people may be living with dementia in 2050. Alzheimer’s disease (AD) is the leading cause of dement…
There is currently considerable interest in the development of medicines that would enhance endocannabinoid-induced “autoprotection”, for example through inhibition of endocannabinoid metabolizing enzymes or cellular uptake processes or that would oppose endocannabinoid-induced “autoimpairment”. This volume describes the physiology, pathophysiology and pharmacology of the endocannabinoi…
In prosthetic devices, electrodes are the interfaces between the implant system and the body. Electrodes may be used for neural stimulation or neural signal recording according to the application. The signals to be recorded are typically small, i.e. some tens of microvolts for single pulse activity to a maximum amplitude of around 80 mV for intracellular potentials measured for example by f…