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Proteases in Apoptosis; Pathways, Protocols and Translational Advances
Kata pengantar; Sebagai kepala salah satu rumah sakit kanker paling bergengsi di Asia, saya sangat menyadari peran penting kematian sel terprogram (PCD) dalam menjaga homeostatis seluler tubuh dengan menghilangkan miliaran sel berlebih. Proses alami ini menghadirkan penghalang yang signifikan terhadap perkembangan kanker. Menyadari potensi besar molekul apoptosis sebagai target terapi, saya yak…
- Edition
- -
- ISBN/ISSN
- 978-3-319-19497-4
- Collation
- -
- Series Title
- -
- Call Number
- 571.59 BOS p
Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy: New Perspectives an…
This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic …
- Edition
- Ed. 1
- ISBN/ISSN
- 978-3-319-39406-0
- Collation
- XVII, 247
- Series Title
- Advances in Experimental Medicine and Biology
- Call Number
- 616.994 APO a
Dynamics of cell fate decision mediated by the interplay of autophagy and apo…
This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to…
- Edition
- -
- ISBN/ISSN
- 9783319149622
- Collation
- -
- Series Title
- -
- Call Number
- 571.64
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