It is almost impossible to find a plague-related news item today that is not accompanied by an image of a rat. The best-known carriers of zoonotic diseases, rats are so closely identified with plague that research articles about the role of other mammals in the spread or maintenance of the disease are met with enthusiasm in the media—and in some cases mistakenly hailed as exonerating rats fro…
Obesity is a subcortical brain disease characterised by the pathognomonic symptoms of excessive hunger and/or reduced satiation after a meal. Distinct subtypes of obesity are recognised, although the rising incidence of polygenic obesity resulting from incompletely elucidated gene-environment interactions is of greatest public health concern. Obesity complications are well documented; their rev…
The call for a One Health approach that transcends species and disciplinary boundaries assumes that human and veterinary medicine are discrete, distinctive domains whose separation must be overcome to achieve health benefits for all. This paper will problematize this assumption by demonstrating that until relatively recently, their boundaries were extremely fluid. Referring to specific examples…
Tropical diseases affect millions of people throughout the world and particularly in the developing countries. The millennium development goals had specifically targeted HIV/AIDS and Malaria for substantial reduction as well as Tuberculosis while many other tropical diseases have been neglected. The new sustainable development goals have not made such distinction and have targeted all diseases …
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researcher…
Parkinson’s disease (PD) is a progressive neurodegenerative disorder, characterized by motor and non-motor symptoms due to the degeneration of the pars compacta of the substantia nigra (SNc) with dopaminergic denervation of the striatum. Although the diagnosis of PD is principally based on a clinical assessment, great efforts have been expended over the past two decades to evaluate reliab…
Virocontrol involves biocontrol of pathogens via hypovirulence-causing mycoviruses. This chapter discusses the characteristics of mycoviruses and the conditions that need to be met to make a successful virocontrol agent. The chapter describes one of the success stories so far, that of virocontrol of Cryphonectria parasitica, the chestnut blight pathogen. The chapter ends by reviewing future tre…
Aging is a dynamic and irreversible physiological process, which leads to the progressive decline of biological functions involving all tissues and organs, due to a variety of endogenous and environmental factors. Metabolic changes are some of the hallmarks of aging and the alteration of metabolic pathways may accelerate the process and the onset of age-related diseases.
Background and Objectives: Aspirin (ASA) is a commonly used antithrombotic drug that has been demonstrated to reduce venous thromboembolism. The aim was to analyze if geriatric COVID-19 patients undergoing a 100 mg/day Aspirin (ASA) treatment prior to hospitalization differ in hospital outcome compared to patients without previous ASA therapy. Materials and Methods: An observational retrosp…
A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and di…