Amyotrophic lateral sclerosis (ALS), yang dideskripsikan sejak tahun 1869 oleh Jean Martin Charcot, adalah penyakit neurodegeneratif yang menghancurkan yang ditandai dengan hilangnya neuron motorik atas dan bawah secara selektif dan progresif pada korteks serebral, batang otak, dan sumsum tulang belakang. Proses kognitif tidak terpengaruh dan bukan hanya akibat penuaan karena dapat terjadi pada…
Multiple sclerosis (MS) adalah salah satu gangguan neurologis yang paling umum pada orang dewasa muda. Etiologi MS tidak diketahui, tetapi secara umum diterima bahwa MS bersifat autoimun. Pengetahuan kami tentang patogenesis MS telah meningkat pesat dalam dekade terakhir melalui studi klinis dan penggunaan experimental autoimmune encephalomyelitis (EAE), model yang telah banyak digunakan untuk …
Cancer is a leading cause of death worldwide, claiming millions of lives each year. Cancer biology is an essential research field to understand how cancer develops, evolves, and responds to therapy. By taking advantage of a series of “omics” technologies (e.g., genomics, transcriptomics, and epigenomics), computational methods in bioinformatics and machine learning can help scientists and r…
In The Genealogy of a Gene, Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied "genealogy" of CCR5 -- intellectual property, natural selection, Big and Small Pharma, human diversity studies, personalized medicine, ancestry studies, and race and genomics -- Jackson links a myriad of diverse topics. The hi…
"A Bradford book."The field of evolutionary biology arose from the desire to understand the origin and diversity of biological forms. In recent years, however, evolutionary genetics, with its focus on the modification and inheritance of presumed genetic programs, has all but overwhelmed other aspects of evolutionary biology. This has led to the neglect of the study of the generative origins of …
A comparative study of genetic testing for breast and ovarian cancer in the United States and Britain that shows the importance of national context in the development and use of science and technology even in an era of globalization.OCLC-licensed vendor bibliographic record.
This title begins the inquiry into the evolution of the collective sensitivities of life. Scientist-scholars from a range of fields - including biochemistry, cell biology, history of science, family therapy, genetics, microbial ecology, and primatology - trace the emergence and evolution of consciousness.
Contributors examine how regulatory & institutional environments affect the functioning of markets & propose reforms, arguing that quantitative methods should be used to guide policy & to reform rules & regulations. These essays offer methodologies for the assessment of policy alternatives.OCLC-licensed vendor bibliographic record.
A cultural history of gigantism in architecture and digital culture, from the Eiffel Tower to the World Trade Center. The gigantic is everywhere, and gigantism is manifest in everything from excessively tall skyscrapers to globe-spanning digital networks. In this book, Henriette Steiner and Kristin Veel map and critique the trajectory of gigantism in architecture and digital culture--the conver…